Characterizing pelvic vein flow using advanced MRI techniques
Official title: Pelvic Vein Quantitative Flow Characterization Using 2D and 4D Flow MRI
Run by University of Massachusetts, Worcester · NCT06888024 · Data updated 2026-11-12
This study is testing how blood flows in the pelvic veins of healthy people, those with May-Thurner syndrome, and patients with iliac stents to better understand these conditions.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 89 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | University of Massachusetts, Worcester Academic / other |
| Locations | 1 site (Worcester, Massachusetts) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | January 1, 2029 |
| Study ends | April 1, 2029 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT06888024 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with May-Thurner syndrome, those who have had iliac stent placement, or healthy individuals without venous disease.
✕Probably not a fit
Patients with contraindications to MRI or those with a history of pelvic or iliac venous disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to quantitatively analyze the flow in pelvic venous structures through 2D and 4D flow MRI. It includes three arms: one to establish baseline flow characteristics in healthy individuals, another to assess flow in patients with May-Thurner syndrome, and a third for those who have undergone iliac stent placement. The goal is to create physiologic and pathologic parameters that can inform future computational fluid dynamics analyses.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and treatment of iliac venous diseases, potentially leading to improved patient outcomes.
How similar studies have gone: While the specific approach of using 2D and 4D flow MRI for this purpose may be novel, similar studies have shown promise in characterizing venous flow dynamics.
Who can join: the full rules
Show full inclusion / exclusion criteria
Arm 1: Inclusion Criteria: • No self-reported history of pelvic or iliac venous disease or associated symptoms Exclusion Criteria: * History of pelvic or iliac venous disease or intervention * Contraindication to MRI examination * Prisoners * Subjects ≤ 18 years of age * Pregnant women * Adults unable to provide informed consent Arm 2: Inclusion Criteria: • Clinical symptoms or imaging findings compatible with left iliac vein compression syndrome Exclusion Criteria: * History of pelvic or iliac venous intervention * Contraindication to MRI examination * Prisoners * Subjects ≤ 18 years of age * Pregnant women * Adults unable to provide informed consent Arm 3: Inclusion Criteria: • History of left iliac vein stent placement Exclusion Criteria: * Contraindication to MRI examination * Prisoners * Subjects ≤ 18 years of age * Pregnant women * Adults unable to provide informed consent
Where it's running
-
University of Massachusetts
Worcester, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Ningcheng Li, MD — UMass Chan Medical School
- Study coordinator: Noelle Bodkin
- Email: noelle.bodkin@umassmed.edu
- Phone: 774-441-8442.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.