Characterizing patient populations with pediatric hydrocephalus
HCRN Core Data Project: Characterizing Patient Populations in the Hydrocephalus Clinical Research Network (HCRN)
This study is collecting information about children with hydrocephalus to see how they are treated and how the condition changes over time, so we can improve care for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1400 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | University of Utah Academic / other |
| Locations | 14 sites (Birmingham, Alabama and 13 other locations) |
| Trial ID | NCT00670735 on ClinicalTrials.gov |
What this trial studies
The Hydrocephalus Clinical Research Network (HCRN) aims to gather comprehensive data on pediatric hydrocephalus through a multi-institutional approach. This observational project collects information on all neurosurgical events related to hydrocephalus from various clinical centers, creating a robust database for researchers. The data will help in understanding treatment variability, disease progression, and current practices, ultimately guiding better therapeutic interventions for affected children.
Who should consider this trial
Good fit: Ideal candidates for this project are children diagnosed with pediatric hydrocephalus who have undergone neurosurgical interventions.
Not a fit: Patients who have only received temporary cerebrospinal fluid diversion procedures, such as external ventricular drains, will not benefit from this study.
Why it matters
Potential benefit: If successful, this project could lead to improved treatment strategies and outcomes for children with hydrocephalus.
How similar studies have performed: Other studies focusing on pediatric hydrocephalus have shown promise in improving understanding and treatment, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Information for all neurosurgical hydrocephalus patient events will be obtained from each HCRN Clinical Center and will be placed continuously into the Core Data Project. The first calendar year will be 2008, and data collection will continue for the duration of the existence of the HCRN. Neurosurgical hydrocephalus patient events include any operation for the treatment of documented hydrocephalus including the following: * Ventriculoperitoneal shunt * Ventriculoatrial shunt * Ventriculopleural shunt * Arachnoid cyst shunts * Subdural shunts * Lumboperitoneal shunts * Shunts replaced after treatment of infection * Shunts exposed during an operations but not revised * Endoscopic third ventriculostomies * Ommaya reservoir(s) * Ventricular access devices/reservoirs * Subgaleal shunts. Exclusion Criteria: The following temporary cerebrospinal fluid (CSF) diversion procedures will not be included in the Core Date Project: • External ventricular drain(s)
Where this trial is running
Birmingham, Alabama and 13 other locations
- Children's Hospital of Alabama, University of Alabama — Birmingham, Alabama, United States (Recruiting)
- Children's Hospital of Los Angeles — Los Angeles, California, United States (Recruiting)
- Children's Hospital Colorado — Aurora, Colorado, United States (Recruiting)
- Johns Hopkins Children's Center — Baltimore, Maryland, United States (Not_yet_recruiting)
- St. Louis Children's Hospital — St Louis, Missouri, United States (Recruiting)
- Nationwide Children's Hospital — Columbus, Ohio, United States (Recruiting)
- Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania, United States (Recruiting)
- Monroe Carell Jr. Children's Hospital at Vanderbilt — Nashville, Tennessee, United States (Recruiting)
- Texas Children's Hospital — Houston, Texas, United States (Recruiting)
- Primary Children's Hospital — Salt Lake City, Utah, United States (Recruiting)
- Seattle Children's Hospital — Seattle, Washington, United States (Recruiting)
- Alberta Children's Hospital — Calgary, Alberta, Canada (Recruiting)
- British Columbia Children's Hospital — Vancouver, British Columbia, Canada (Recruiting)
- Sick Children's Hospital — Toronto, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Abhaya Kulkarni, MD, PhD — Sick Children's Hospital, Toronto, Ontario
- Study coordinator: Marcie Langley
- Email: marcie.langley@hsc.utah.edu
- Phone: 801-662-5364
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.