Characterizing cells from musculoskeletal tissues to improve treatment for joint disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on isolating and characterizing tissue-resident cells from various musculoskeletal and associated connective tissues, such as cartilage and bone, to explore new treatment strategies for degenerative and inflammatory musculoskeletal diseases. The researchers will compare the isolated cells based on their phenotypic and functional characteristics after exposure to inflammatory elements and treatments. Additionally, the study aims to correlate the properties of these cells with the clinical profiles of patients undergoing elective surgeries, such as joint replacements or ligament repairs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* males and females

  * 18 years old
* patients undergoing elective surgery at IRCCS Istituto Ortopedico Galeazzi among which joint surgery (including hip or knee replacement), or anterior cruciate ligament (ACL) reconstruction or rotator cuff repair

Exclusion Criteria:

* age \< 18 years old
* patients unable to sign the Informed Consent
* positivity to virological test (HIV, HCV, HBV, TPHA)

Where it's running

• IRCCS Istituto Ortopedico Galeazzi
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Direzione Scientifica
• Email: direzionescientifica.iog@grupposandonato.it
• Phone: 00390266214048

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.