Changing smoking behavior in LGBTQ+ young adults through targeted messaging

The Effect of Nicotine and Tobacco Message Framing on Use Among Diverse Groups of Young Adults: Aim 3 Randomized Control Trial (RCT)

Not applicable Interventional Ohio State University Comprehensive Cancer Center · NCT06644664

This study is testing if different types of messages can help LGBTQ+ young adults reduce their smoking and tobacco use over six weeks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years to 35 Years
SexAll
SponsorOhio State University Comprehensive Cancer Center Academic / other
Locations1 site (Columbus, Ohio)
Trial IDNCT06644664 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates how different messaging strategies can influence smoking behaviors among LGBTQ+ young adults who use nicotine and/or tobacco products. Participants will receive mobile multimedia messaging (MMS) with either absolute or relative risk information about polytobacco use, or control messages about UV exposure, over a six-week period. The study aims to assess the feasibility of delivering these messages and to estimate their effects on participants' risk perceptions and tobacco use over time. Follow-up assessments will occur at 6 and 12 weeks post-intervention to evaluate changes in smoking behavior.

Who should consider this trial

Good fit: Ideal candidates are LGBTQ+ young adults aged 18-35 who currently use electronic nicotine delivery systems or combustible tobacco.

Not a fit: Patients who do not identify as LGBTQ+ or do not currently use tobacco products may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective smoking cessation strategies tailored for LGBTQ+ young adults.

How similar studies have performed: Other studies have shown promise in using targeted messaging to influence health behaviors, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-35 years old
* Self-identify as LGBTQ+
* Able to speak English fluently
* An ever user of ENDS and combustible tobacco who currently use ENDS, combustible cigarettes, or both ENDS and combustible cigarettes
* Currently reside in the United States (US)
* Have a mobile phone through a U.S. carrier with MMS messaging and can send and receive text messages for study participation
* Access to the internet with Zoom capabilities

Exclusion Criteria:

* Have a landline or Voice Over Internet Protocol (VOIP) phone number

Where this trial is running

Columbus, Ohio

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Tobacco-Related CarcinomaSexual and Gender MinoritiesHealth CommunicationTobacco ProductsCigarettesElectronic Nicotine Delivery SystemsE-cigarettesyoung adult
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.