Cervical spine treatment for concussion patients with neck pain

Cervical Spine Focused Treatment for Patients With Persistent Concussion Symptoms and Neck Pain: Pilot Study

Not applicable Interventional University of Pittsburgh · NCT06616272

This study is testing whether early neck treatment can help people with ongoing concussion symptoms and neck pain feel better compared to just standard care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages12 Years to 50 Years
SexAll
SponsorUniversity of Pittsburgh Academic / other
Locations4 sites (Pittsburgh, Pennsylvania and 3 other locations)
Trial IDNCT06616272 on ClinicalTrials.gov

What this trial studies

This study assesses the feasibility of recruiting and randomizing patients who have persistent concussion symptoms and neck pain to receive early cervical rehabilitation in addition to standard concussion care. Participants will be divided into two groups: one receiving early cervical spine treatment and the other receiving standard care followed by delayed cervical treatment. The study aims to identify barriers in the current workflow at the concussion clinic to allow for earlier intervention. The primary endpoint will be evaluated after 4 weeks of cervical rehabilitation, with a total participation duration of 8 weeks.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with a concussion who also experience moderate to severe neck pain or difficulty moving their neck.

Not a fit: Patients with a history of recent concussions, prior cervical spine surgery, or those with specific exclusion criteria may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved recovery outcomes for patients suffering from both concussion symptoms and neck pain.

How similar studies have performed: While this approach is novel in its focus on early cervical rehabilitation for concussion patients, similar studies have shown promise in addressing related symptoms.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed concussion
* Patient endorses neck pain OR difficulty moving their neck (moderate or severe; score of 2 or 3 for items 16 and 25 from concussion CP screen)
* Willingness to be randomized
* 8-90 days post injury
* English Speaking

Exclusion Criteria:

* Previous concussion within the past 6 months
* Prior history of ischemic/vascular events
* Previous treatment for current symptoms
* Prior treatment for neck pain/headaches in the past year
* Workers' compensation claim and/or litigation associated with injury
* Diagnosed substance use disorder
* Prior cervical spine surgery
* Prior fracture and or dislocation/subluxation of the cervical spine
* Diagnosed inflammatory arthritis

Where this trial is running

Pittsburgh, Pennsylvania and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Brain ConcussionNeck Painconcussion carecervical rehabilitationneck pain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.