Cervical Spinal Cord Signal Abnormalities in Patients with Neck Pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study enrolls up to 400 adults with cervical radicular pain at Ankara Bilkent City Hospital. Researchers will record neurological findings, Hoffmann sign results, and routine cervical MRI findings to determine how often spinal cord signal abnormalities occur, including myelomalacia. Secondary goals include understanding how clinical and imaging factors relate to treatment decisions and whether Hoffmann sign predicts spinal cord abnormalities or surgical referrals. No interventions beyond standard clinical care and imaging are performed. The study relies on data collected during routine visits and MRI assessments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Presentation to the pain clinic with cervical radicular pain
* Clinical symptoms and/or examination findings consistent with cervical nerve root involvement
* Availability of a cervical magnetic resonance imaging (MRI) examination suitable for evaluation
* Completion of standardized neurological examination at the initial visit
* Ability and willingness to provide written informed consent

Exclusion Criteria:

* Previous cervical spine surgery
* Acute cervical spine trauma
* Known cervical spinal malignancy
* Active spinal infection
* Known inflammatory, demyelinating, or other non-degenerative spinal cord disease
* Severe cognitive impairment or communication difficulty preventing reliable clinical assessment
* Inadequate or non-diagnostic cervical MRI quality
* Refusal to participate

Where it's running

• Ankara Bilkent City Hospital
  Ankara, Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ülkü Sabuncu, Assoc prof
• Email: sabuncuulku@gmail.com
• Phone: 905337085212

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.