Cervical mobilization plus vestibular rehabilitation for dizziness and balance in Meniere's disease
Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere's Disease
This will test whether adding cervical mobilization to vestibular rehabilitation helps people with Meniere's disease who have dizziness, balance problems, or neck-related symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 33 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Abant Izzet Baysal University Academic / other |
| Locations | 1 site (Afyonkarahisar, Afyonkarahisar) |
| Trial ID | NCT07272473 on ClinicalTrials.gov |
What this trial studies
Adults with unilateral or bilateral Meniere's disease will be stratified and randomized into three groups at an ENT outpatient clinic in Turkey: routine betahistine alone, betahistine plus 30 minutes of vestibular rehabilitation (VR), or betahistine plus 20 minutes of VR and 10 minutes of cervical mobilization. The intervention period is six weeks, with VR including progressive adaptation, habituation, and compensation exercises that increase in difficulty each week. Outcomes include validated patient-reported scales (Dizziness Handicap Inventory, Vertigo Symptom Scale, Neck Disability Index, International Tinnitus Inventory) and objective balance and joint position sense measures. The trial compares whether adding cervical mobilization provides additional benefit over VR alone or medication alone.
Who should consider this trial
Good fit: Adults aged 18–60 with a definitive unilateral or bilateral diagnosis of Meniere's disease, fluctuating or chronic imbalance for at least 3 months, cognitive function sufficient for rehab (MMSE ≥ 24), and willing to consent are ideal candidates.
Not a fit: Those with vertigo from other causes, acute medical or neurological conditions, recent orthopedic surgery, planned surgical interventions, cervical spine instability, acute cervical trauma, vertebral artery insufficiency, or significant cognitive impairment are unlikely to benefit or be eligible.
Why it matters
Potential benefit: If successful, the combined approach could reduce dizziness and improve balance and neck-related symptoms in people with Meniere's disease.
How similar studies have performed: Vestibular rehabilitation has shown benefit for vestibular disorders generally, but combining cervical mobilization specifically for Meniere's disease is relatively novel and has limited prior evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Definitive clinical diagnosis of unilateral or bilateral Meniere's disease * Age between 18 and 60 years * Presence of fluctuating symptoms or chronic imbalance for at least 3 months * Cognitive ability to participate in balance rehabilitation tasks (Mini Mental State Examination score ≥ 24) * Willingness to participate in the study and provide informed consent Exclusion Criteria: * Diagnosis of vertigo not associated with Meniere's disease * Presence of another acute medical condition * Neurological, psychological, or cognitive dysfunction * History of orthopedic surgery within the last 3 months * Planned surgical intervention during the rehabilitation program * Cervical spine instability * Acute cervical trauma * Vertebral artery insufficiency
Where this trial is running
Afyonkarahisar, Afyonkarahisar
- Afyonkarahisar Health Sciences University Health Application and Research Center, Ear, Nose and Throat Polyclinic — Afyonkarahisar, Afyonkarahisar, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: nurgul sarı, Master's Degree
- Email: nurgulsen12@gmail.com
- Phone: +905344527440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.