Cervical cancer screening for older women

Reducing the Burden of Cervical Cancer Among Older Women by Expanding the Screening Age and Offering HPV Self-sampling

Observational University of Aarhus · NCT04114968

This study tests if using HPV self-sampling for cervical cancer screening is effective for women aged 65 to 69 who haven't been screened in the last five years.

Quick facts

Study typeObservational
Enrollment20000 (estimated)
Ages65 Years to 69 Years
SexFemale
SponsorUniversity of Aarhus Academic / other
Locations1 site (Randers, Randers NØ)
Trial IDNCT04114968 on ClinicalTrials.gov

What this trial studies

This study evaluates the feasibility and effectiveness of including women aged 65 to 69 in the Danish cervical cancer screening program. It focuses on the use of HPV self-sampling as a screening method for this age group. The study is a nationwide population-based cohort study that compares an intervention group receiving HPV-based screening to a control group receiving standard care. Eligible participants are women who have not had a cervical cytology sample or screening invitation in the last five years.

Who should consider this trial

Good fit: Ideal candidates for this study are Danish women aged 65 to 69 who have not been screened for cervical cancer in the past five years.

Not a fit: Patients who have had a hysterectomy or those who are not residents of Denmark may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve early detection of cervical cancer in older women, potentially leading to better health outcomes.

How similar studies have performed: Other studies have shown success with HPV self-sampling in cervical cancer screening, indicating a promising approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 65 to 69 years;
* Resident in Denmark
* No record of a cervical cytology or screening invitation in the past 5 years
* Not registered as ineligible for screening

Exclusion Criteria:

* Death
* Migration to or from Denmark
* Moving to or from the CDR
* Residing in the CDR, but having GP in another region
* A record of hysterectomy

Where this trial is running

Randers, Randers NØ

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Uterine Cervical NeoplasmUterine NeoplasmUterine Cervical DiseaseMass ScreeningHPV self-sampling, cervical cancer screening in older women
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.