Cerebral Venous Thrombosis Cohort: Features and Treatments in China
Official title: Cerebral Venous Thrombosis Cohort Study in China Mainland
Run by Capital Medical University · NCT03919305 · Data updated 2026-11-12
This study follows people with cerebral venous thrombosis in China to see how the condition presents, progresses, and responds to current treatments, while collecting blood and spinal fluid to explore biomarkers.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 3000 (estimated) |
| Sponsor | Capital Medical University Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | January 1, 2019 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2026 |
| Registry record updated | June 2, 2026 |
| Trial ID | NCT03919305 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Individuals diagnosed with cerebral venous sinus thrombosis, deep cerebral vein thrombosis, or cortical vein thrombosis confirmed by imaging.
✕Probably not a fit
Patients who do not meet the diagnostic criteria or choose not to participate may not benefit from study findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter cohort study in China aims to describe the clinical features and natural history of cerebral venous thrombosis across 31 provinces. Researchers will collect blood and cerebrospinal fluid samples after enrollment to investigate pathological mechanisms and identify potential biomarkers. Participants will be followed at 1, 3, 6, and 12 months to assess prognosis and therapeutic outcomes. The study uses observational methods and analyzes real-world treatment patterns without an experimental intervention.
Why it matters
Potential benefit: Findings could improve understanding of CVT biology and how current therapies work, potentially guiding future care.
How similar studies have gone: Previous observational cohorts have provided valuable real-world insights into CVT; this study adds biomarker exploration and nationwide scope.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: • Cerebral venous sinus thrombosis, deep cerebral vein thrombosis and cortical vein thrombosis diagnosed by digital subtraction angiography (DSA), magnetic resonance venography (MRV), computed tomography venography (CTV) or high-resolution magnetic resonance imaging (HR-MRI). Exclusion Criteria: • None of the patient, trustee or immediate family members signed the informed consent.
Where it's running
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Xuanwu Hospital, Capital Medical University
Beijing, China Recruiting
Study contacts
- Principal investigator: Xunming Ji, MD, PhD — Xuanwu Hospital, Beijing
- Study coordinator: Min Li, MD, PhD
- Email: 812879698@qq.com
- Phone: +86-18701519698
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Danang Cerebral Venous Thrombosis Registry
This registry collects information on adults with cerebral venous thrombosis admitted to Danang Hospital to see how the condition presents, what imaging shows, risk factors, and how patients recover.
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Endovascular treatment plus anticoagulation for severe CVST in the MENA region
This trial tests whether adding endovascular thrombectomy to standard anticoagulation helps adults with severe cerebral venous sinus thrombosis see better outcomes.
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Investigating cerebral vein thrombosis in Norway
This study looks at how common cerebral vein thrombosis is in Norway, what causes it, how it's treated, and what happens to patients in the long run.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.