Cerebral oxygen monitoring during orthopedic surgery in the semi-sitting (beach-chair) position
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
We will see if noninvasive brain oxygen readings (NIRS) match routine heart rate, invasive arterial pressure, end-tidal CO2, and arterial blood gas changes in adults having orthopedic surgery in the semi-sitting position.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Akdeniz University Academic / other |
| Locations | 2 sites (Antalya and 1 other locations) |
| Trial ID | NCT07270341 on ClinicalTrials.gov |
What this trial studies
This prospective observational cohort continuously records cerebral oxygenation with near-infrared spectroscopy (NIRS) alongside routine noninvasive monitors and invasive arterial pressure during orthopedic operations performed in the semi-sitting (beach-chair) position. Investigators will compare NIRS values to heart rate, invasive mean arterial pressure, end-tidal carbon dioxide, and arterial blood gas results to determine correlations and temporal relationships. The study will also examine whether comorbidities such as diabetes, obesity, and hypertension are associated with cerebral perfusion parameters. No experimental interventions are applied beyond standard anesthetic and surgical care.
Who should consider this trial
Good fit: Adults (age ≥18) who are ASA physical status I–III, scheduled for orthopedic surgery in the semi-sitting position at Akdeniz University Hospital, and who provide informed consent.
Not a fit: Patients with prior cerebral ischemia, head trauma, previous neurosurgery, documented carotid stenosis ≥90%, prior neck surgery, children, or those who do not consent are unlikely to benefit from this observational monitoring protocol.
Why it matters
Potential benefit: If successful, the results could help clinicians detect early cerebral hypoperfusion and improve monitoring to reduce neurological complications during beach-chair orthopedic surgery.
How similar studies have performed: Previous studies using NIRS during sitting or beach-chair procedures have shown it can detect cerebral desaturation events, but correlations with standard hemodynamic measures have been inconsistent and are not fully established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled for orthopedic surgery in the semi-sitting position * ASA physical status I-III * Voluntary participation with informed consent Exclusion Criteria: * Patients younger than 18 years * Patients who do not provide consent * History of cerebral ischemia * History of head trauma * Previous neurosurgical intervention * Documented carotid stenosis ≥90% * Previous neck surgery
Where this trial is running
Antalya and 1 other locations
- Akdeniz University Hospital — Antalya, Turkey (Türkiye) (Recruiting)
- Akdeniz University Hospital — Antalya, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Nesil Coşkunfırat, Prof Dr (M.D.)
- Email: nesildgr@yahoo.com
- Phone: +905326873426
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.