Clinical trial Recruiting at 1 site Interventional Ages 21 and up

CCC model to help serious illness conversations and care in cancer

Official title: Evaluating the Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer

Run by National Cancer Centre, Singapore · NCT07733973 · Data updated 2026-11-12

This trial tests a Communication and Care Coordinator (CCC) model to see if it can improve communication about serious illness and care planning for cancer patients.

Quick facts

Study typeInterventional
Ages21 Years and up
SexAll
Enrollment560 (estimated)
SponsorNational Cancer Centre, Singapore
Academic / other
Locations1 site (Singapore)
StatusRecruiting
StartedNovember 5, 2026
Main results expectedJune 30, 2028
Study endsJune 30, 2029
Registry record updatedNovember 10, 2026
Trial IDNCT07733973 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 21 or older with advanced cancer or high-risk recurrence, able to speak English or Chinese, treated by NCCS oncologists of associate consultant level or higher.

Probably not a fit

Patients who prefer standard care or who are not candidates for enhanced communication support may not experience additional benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study uses a stepped wedge cluster randomized design at a national cancer center to compare the CCC intervention with usual care. It aims to determine whether the CCC model improves patient outcomes, increases documentation of serious illness conversations and advance care planning, and is acceptable to patients and clinicians. The intervention deploys dedicated coordinators to support oncology teams in facilitating timely, patient-centered communication about goals of care. Outcomes include feasibility of implementation and potential impact on patient well-being and care documentation. Enrollment includes adults with advanced or high-risk cancer who can speak English or Chinese, with participating oncologists at NCC Singapore.

Why it matters

Potential benefit: If successful, the CCC model could enable more timely and meaningful conversations about goals of care and improve documentation and care aligned with patient preferences.

How similar studies have gone: Previous work in similar coordination models has shown promise in improving communication and planning, but this specific CCC approach in Singapore is novel and exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patient Participants

* Aged 21 and above
* Diagnosed with (a) advanced cancer (stage 3 or 4) or (b) non-advanced cancer, but at high risk of recurrence
* Able to speak English or Chinese, irrespective of race

Clinicians

* Oncologists who are at least of designation of associate consultant and above in NCCS

Exclusion Criteria:

Patient Participants

* Disoriented and thus not able to sign informed consent
* Diagnosed with untreated hearing or visual loss or psychiatric illness
* Active suicidal ideation

Clinicians

* Overseas/not practising in Singapore for a significant amount of time

Where it's running

  • National Cancer Center, Singapore
    Singapore, Singapore
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.