CBT-based weight loss program for obese patients with depression
CBT-Based Weight Loss Treatment Model in Obese Patients With Comorbid Depression. Effect on Eating Behavior, Weight Loss, Mood, and Risk of Coronary Artery Disease and Diabetes.
This study is testing whether a year-long weight loss program using Cognitive Behavioral Therapy can help obese adults with depression improve their eating habits, lose weight, and feel better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Kuopio University Hospital Academic / other |
| Locations | 1 site (Kuopio) |
| Trial ID | NCT04513587 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of a Cognitive Behavioral Therapy (CBT)-based weight loss program on eating behavior, weight loss, mood symptoms, and the risk of coronary heart disease and type 2 diabetes in obese patients with comorbid depression. It is a randomized controlled trial involving 80 adult participants with a BMI greater than 35 and diagnosed depression, divided into an intervention group receiving the CBT program and a control group. The intervention consists of 52 weeks of group counseling aimed at modifying eating behaviors and lifestyle factors. Participants will be followed for one year to assess long-term outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-65 with a BMI over 35 and a diagnosis of depression.
Not a fit: Patients with severe psychiatric conditions, psychotic disorders, or significant medical illnesses contraindicating weight loss may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly improve weight management and mental health outcomes for patients with obesity and depression.
How similar studies have performed: Previous studies have shown promising results for CBT-based interventions in weight management, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-65 years * Diagnosed depression ( F32.0, F32.1, F32.2, F33.0, F33.1, F33.2) * BMI \> 35 Exclusion Criteria: * Psychotic disorder, schizoaffective disorder, psychotic depression or bipolar disorder * Severe current substance abuse * Serious psychiatric condition (i.e self-destructive or impulsive behavior) * Clinically significant illness contraindicating weight loss (i.e cancer or severe heart disease) * Simultaneous participation in another weight loss program * Severe vision, hearing, motoric deficiency
Where this trial is running
Kuopio
- Kuopio University Hospital — Kuopio, Finland (Recruiting)
Study contacts
- Principal investigator: Anna-Maria Teeriniemi, PhD — Kuopio University Hospital
- Study coordinator: Anna-Maria Teeriniemi, PhD
- Email: anna-maria.teeriniemi@kuh.fi
- Phone: +358447113148
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.