Causes and outcomes of coronary artery disease over time
Causation And Prognosis Analyses of Coronary Artery dIseases: a longiTudinal Cohort studY
We will follow adults with coronary artery disease to see if certain risk factors are linked to dying from any cause or from heart-related causes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Trial ID | NCT07480512 on ClinicalTrials.gov |
What this trial studies
This single-center historical prospective cohort will include adults diagnosed with coronary artery disease, including stable and unstable angina, NSTEMI, STEMI, latent disease, and ischemic cardiomyopathy. Researchers will use existing clinical records from The First Affiliated Hospital of Sun Yat-sen University to assemble the cohort and will follow outcomes over time, with primary endpoints of all-cause and cardiovascular mortality. Analyses will examine associations between established or suspected cardiovascular risk factors and mortality outcomes in this real-world clinical population. The goal is to clarify which patient characteristics are most strongly linked to long-term survival after coronary artery disease.
Who should consider this trial
Good fit: Adults over 18 with a clinical diagnosis of coronary artery disease (including angina, NSTEMI, STEMI, latent disease, or ischemic cardiomyopathy) who are treated or followed at the study hospital and can provide consent.
Not a fit: People without coronary artery disease, those treated elsewhere who cannot be followed, or individuals unable to provide informed consent are unlikely to benefit from participation.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify patients at higher risk of death and target preventive or monitoring strategies to improve outcomes.
How similar studies have performed: Previous cohort studies have successfully linked cardiovascular risk factors to mortality, so this approach is well-established rather than entirely novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years old; * Patients with clinical diagnosis of coronary artery diseases, including stable angina pectoris, unstable angina pectoris, non-ST-segment elevation myocardial infarction, ST-segment elevation myocardial infarction, latent coronary artery diseases and ischemic cardiomyopathy. Exclusion Criteria: * Patients unable to provide informed consent.
Where this trial is running
Guangzhou, Guangdong
- The First Affiliated Hospital, Sun Yat-sen Univerity — Guangzhou, Guangdong, China (Recruiting)
Study contacts
- Study coordinator: Xiaodong Zhuang, Professor
- Email: zhuangxd3@mail.sysu.edu.cn
- Phone: +8613760755035
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.