Causes and outcomes of coronary artery disease over time
Official title: Causation And Prognosis Analyses of Coronary Artery dIseases: a longiTudinal Cohort studY
Run by Sun Yat-sen University · NCT07480512 · Data updated 2026-11-12
We will follow adults with coronary artery disease to see if certain risk factors are linked to dying from any cause or from heart-related causes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30000 (estimated) |
| Sponsor | Sun Yat-sen University Academic / other |
| Locations | 1 site (Guangzhou, Guangdong) |
| Status | Recruiting |
| Started | January 1, 2013 |
| Main results expected | December 31, 2032 |
| Study ends | December 31, 2032 |
| Registry record updated | March 18, 2026 |
| Trial ID | NCT07480512 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with a clinical diagnosis of coronary artery disease (including angina, NSTEMI, STEMI, latent disease, or ischemic cardiomyopathy) who are treated or followed at the study hospital and can provide consent.
✕Probably not a fit
People without coronary artery disease, those treated elsewhere who cannot be followed, or individuals unable to provide informed consent are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-center historical prospective cohort will include adults diagnosed with coronary artery disease, including stable and unstable angina, NSTEMI, STEMI, latent disease, and ischemic cardiomyopathy. Researchers will use existing clinical records from The First Affiliated Hospital of Sun Yat-sen University to assemble the cohort and will follow outcomes over time, with primary endpoints of all-cause and cardiovascular mortality. Analyses will examine associations between established or suspected cardiovascular risk factors and mortality outcomes in this real-world clinical population. The goal is to clarify which patient characteristics are most strongly linked to long-term survival after coronary artery disease.
Why it matters
Potential benefit: If successful, the findings could help clinicians identify patients at higher risk of death and target preventive or monitoring strategies to improve outcomes.
How similar studies have gone: Previous cohort studies have successfully linked cardiovascular risk factors to mortality, so this approach is well-established rather than entirely novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years old; * Patients with clinical diagnosis of coronary artery diseases, including stable angina pectoris, unstable angina pectoris, non-ST-segment elevation myocardial infarction, ST-segment elevation myocardial infarction, latent coronary artery diseases and ischemic cardiomyopathy. Exclusion Criteria: * Patients unable to provide informed consent.
Where it's running
-
The First Affiliated Hospital, Sun Yat-sen Univerity
Guangzhou, Guangdong, China Recruiting
Study contacts
- Study coordinator: Xiaodong Zhuang, Professor
- Email: zhuangxd3@mail.sysu.edu.cn
- Phone: +8613760755035
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.