Clinical trial Recruiting at 3 sites Interventional Ages 18 and up

Caregiver-assisted rehabilitation for stroke patients

Official title: A Caregiver-Assisted Rehabilitation With Strategy Training (CAR-ST) for Stroke Patients With Functional Limitations: A MultiCenter, 3-Arm Randomized Trial

Run by Taipei Medical University · NCT06754566 · Data updated 2026-11-12

This study tests whether involving caregivers in rehabilitation helps stroke survivors improve their daily activities better than standard treatments.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment261 (estimated)
SponsorTaipei Medical University
Academic / other
Locations5 sites (New Taipei City and 4 other locations)
StatusRecruiting
StartedJanuary 17, 2025
Main results expectedJune 30, 2028
Study endsDecember 31, 2028
Registry record updatedFebruary 17, 2025
Trial IDNCT06754566 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include community-dwelling adults diagnosed with ischemic or hemorrhagic stroke who have a modified Rankin Scale score between 2 and 4.

Probably not a fit

Patients receiving palliative care or those with severe cognitive impairments or other major health conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of caregiver-assisted rehabilitation with strategy training (CAR-ST) for improving activity functions in stroke survivors. Participants will be randomly assigned to receive either CAR-ST, strategy training alone, or an education program. The study aims to determine if involving caregivers enhances the rehabilitation outcomes compared to standard approaches. Evaluations will occur at multiple time points to assess the impact on activity performance and overall functional improvements.

Why it matters

Potential benefit: If successful, this approach could significantly enhance the rehabilitation outcomes for stroke survivors, leading to improved daily functioning.

How similar studies have gone: While caregiver involvement in rehabilitation is a promising approach, the specific CAR-ST intervention is novel and has not been extensively tested in previous studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being willing to provide informed consent
* Diagnosis with ischemic and/or hemorrhagic stroke
* Modified Rankin Scale (mRS) ranges from 2 to 4
* Rehabilitation frequency less than 3 days per week
* Having a healthy caregiver

Exclusion Criteria:

* Undergoing palliative care
* Major diseases or severe conditions influencing study participation, such as global aphasia, dementia, multiple organ failure, immobilization due to fracture, etc
* Moderate post-stroke cognitive impairment, with Montreal Cognitive Assessment score \<22
* Pre-stroke mRS \> 1
* Participating in other interventional study concurrently.

Where it's running

  • Taipei Medical University-Shuang Ho Hospital,Ministry of Health and Welfare
    New Taipei City, Taiwan
    Recruiting
  • Taipei Medical University Hospital
    Taipei, Taiwan
    Recruiting
  • Taipei Municipal Wanfang Hospital
    Taipei, Taiwan
    Recruiting
  • Taipei Tzu Chi Hospital
    New Taipei City, Taiwan
    Not yet recruiting
  • National Taiwan University Hospital
    Taipei, Taiwan
    Not yet recruiting

Study contacts

  • Principal investigator: Feng-Heng Chang, ScD — Graduate Institute of Injury Prevention and Control, Taipei Medical University
  • Study coordinator: Chang, ScD
  • Email: ipc@tmu.edu.tw
  • Phone: +886-2-66202589

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.