Cardiovascular Outcomes After Adrenalectomy for Pheochromocytoma and Non-secreting Tumors
Official title: Cardiovascular Complications After Adrenalectomy for Pheochromocytoma and Non-secreting Tumors - A Prospective Observational Multicenter European Study (HEMODYNAMICS)
Run by Central Hospital, Nancy, France · NCT07200245 · Data updated 2026-11-12
This study tests how often and what kinds of cardiovascular problems occur after adrenalectomy for pheochromocytoma or non-secreting tumors.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 522 (estimated) |
| Sponsor | Central Hospital, Nancy, France Academic / other |
| Locations | 1 site (Vandœuvre-lès-Nancy, Lorraine) |
| Status | Recruiting |
| Started | October 1, 2025 |
| Main results expected | October 1, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07200245 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults undergoing adrenalectomy for pheochromocytoma or non-secreting adrenal tumors without malignancy.
✕Probably not a fit
Patients undergoing adrenalectomy for other indications or those not meeting the inclusion criteria may not see direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, multicenter observational study using the EUROCRINE registry to collect real-world data on patients undergoing adrenalectomy for pheochromocytoma or non-secreting tumors. It will add study-specific variables via the my-EUROCRINE module and record preoperative preparation, intraoperative blood pressure events, and cardiovascular outcomes up to day 30. The study uses validated criteria to define hypertensive crises and other cardiovascular events, aiming to reflect routine clinical practice across centers. Consecutive enrollment helps ensure the data represent typical patient experiences and management. Central Hospital, Nancy leads the study with European collaborators.
Why it matters
Potential benefit: If successful, the findings could clarify how preoperative preparation and intraoperative events relate to postoperative cardiovascular risk and guide better perioperative care.
How similar studies have gone: Prior research on pheochromocytoma perioperative management has been limited by small samples; this study expands evidence with multicenter data.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing adrenalectomy for pheochromocytoma * Patients undergoing adrenalectomy for non-secreting tumors. Patients with non-secreting tumors are those with indication for adrenalectomy in the Eurocrine database corresponding to " excluding malignancy ". Exclusion Criteria: * Children and minors (\<18 years). * Pregnant women. * Patients with other indication for adrenalectomy in Eurocrine (i.e. Adrenocortical cancer, Cushing, Primary aldosteronism, Metastasis).
Where it's running
-
CHRU Nancy
Vandœuvre-lès-Nancy, Lorraine, France Recruiting
Study contacts
- Principal investigator: laurent BRUNAUD, MD, PhD — University of Lorraine, CHRU Nancy,
- Study coordinator: laurent BRUNAUD, MD, PhD
- Email: l.brunaud@chru-nancy.fr
- Phone: +33 0383153109
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.