Clinical trial Recruiting at 1 site Interventional Ages 40 and up

Cardiovascular and kidney health screening in AECOPD patients in Hong Kong

Official title: A Prospective Study of Cardiovascular Risk of Patients Admitted for Acute Exacerbation of COPD

Run by Chinese University of Hong Kong · NCT07344285 · Data updated 2026-11-12

This study tests whether screening for hidden heart and kidney disease in people hospitalized for an acute COPD flare can improve care and reduce readmissions.

More COPD trials

Quick facts

Study typeInterventional
Ages40 Years and up
SexAll
Enrollment150 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Shatin, Hong Kong)
StatusRecruiting
StartedJanuary 15, 2026
Main results expectedJanuary 16, 2029
Study endsFebruary 28, 2029
Registry record updatedOctober 21, 2026
Trial IDNCT07344285 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 40 years or older hospitalized for COPD exacerbation with a confirmed COPD diagnosis and able to provide informed consent.

Probably not a fit

Patients without hidden cardiovascular or renal disease or those not followed by the care bundle may not experience additional benefits.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective interventional study evaluates the burden of undiagnosed cardiovascular and renal disease in patients hospitalized for acute exacerbation of COPD at a Hong Kong public hospital. It introduces a COPD discharge care bundle that includes integrated cardiovascular and renal screening to identify undiscovered comorbidities. The study will describe how common these hidden conditions are, explore factors linked to future COPD flare-ups, and compare readmission rates to historical controls to inform integrated cardiopulmonary management. Eligible participants are adults aged 40 and older with a confirmed COPD diagnosis who are admitted for an exacerbation. The lead sponsor is The Chinese University of Hong Kong, with the Prince of Wales Hospital as the participating site.

Why it matters

Potential benefit: If successful, the approach could lead to earlier detection of cardiovascular and renal disease and reduce hospital readmissions for COPD patients.

How similar studies have gone: Prior approaches to integrated cardiopulmonary screening have shown potential benefits, but this specific protocol in AECOPD patients is relatively novel in this setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥40 years
* Patients hospitalized due to COPD exacerbation.
* Patients diagnosed with COPD, a confirmed COPD diagnosis with a specific FEV1/FVC ratio (\<0.70)
* Able to provide informed consent

Exclusion Criteria:

* Pregnant subjects
* Inability to give informed consent
* Cancer patient who are on active chemotherapy or on palliative care

Where it's running

  • Prince of Wales Hospital
    Shatin, Hong Kong, Hong Kong
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.