Cardiac imaging for patients with Fontan circulation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study utilizes cardiac magnetic resonance (CMR) imaging to assess patients with univentricular heart conditions who have undergone Fontan surgery. The study aims to detect early signs of cardiac dysfunction and microvascular issues through advanced non-invasive imaging techniques, allowing for timely intervention before symptoms worsen. Participants will undergo CMR scans with specific imaging protocols and contrast agents to create detailed myocardial stress-perfusion maps. The goal is to improve clinical decision-making regarding treatment and monitoring of these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients who had undergone total cavo-pulmonary connection (TCPC) surgery resulting in Fontan circulation.
* NYHA (New York Heart Assosiation) class I-II.
* Understanding the study information (signed informed consent).
* \>18 years old.

Exclusion Criteria:

* Device therapy (pacemaker, ICD).
* Failing Fontan (NYHA III-IV).
* Kidney failure (GFR\<30ml/h).
* Arrythmia (atrial fibrillation).
* Pregnancy.

Where it's running

• Karolinska University Hospital
  Stockholm, Sweden Recruiting

Study contacts

• Study coordinator: Peder Sorensson, MD, Associate professor
• Email: peder.sorensson@ki.se
• Phone: +46 731 400059

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.