Carbohydrate loading before aortic surgery
Preoperative Oral Carbohydrate Loading in Aortic Surgery
This study is testing if drinking carbohydrate-rich beverages before surgery helps patients having elective aortic surgery recover better and have fewer complications compared to those who fast before the operation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 90 Years |
| Sex | All |
| Sponsor | University of Belgrade Academic / other |
| Locations | 1 site (Belgrade) |
| Trial ID | NCT06349382 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of preoperative oral carbohydrate loading (OCHL) on patients undergoing elective open repair for abdominal aortic aneurysm or Leriche Syndrome. It aims to compare the postoperative outcomes, including ICU stay length, complication rates, and patient well-being, between those receiving carbohydrate-rich beverages and those following a conventional fasting protocol. The trial will enroll approximately 50 patients and collect data on their demographics, clinical history, and postoperative recovery through interviews and medical records.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for elective open surgery for abdominal aortic aneurysm or Leriche Syndrome who can provide informed consent.
Not a fit: Patients with diabetes, severe gastrointestinal disorders, or significant comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance recovery and reduce complications for patients undergoing aortic surgery.
How similar studies have performed: While the benefits of preoperative carbohydrate loading have been documented in other surgical contexts, this specific application in aortic surgery is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Consecutive patients admitted due to elective surgical treatment of abdominal aortic aneurism or Leriche Syndrome. * Patients scheduled to be operated on first on a given day, that is, patients whose surgery will be performed first in the morning. * Personally signed informed consent. Exclusion Criteria: * Patients with diabetes or fasting glucose level above seven mmol/L; * Patients with disorders that prolong gastric emptying (gastroesophageal reflux disease, history of gastrointestinal surgery, hiatus hernia or intestinal obstruction); * Patients with conditions that could potentially prolong the postoperative recovery (severe physical disability, cognitive impairment, autoimmune diseases, severe infection, significant liver and renal failure, or severe psychiatric/mental disorders); * Patients with alcohol/drug abuse * Obese patients with obesity class 3 (BMI ≥ 40 kg/m2); * Patients undergoing emergent surgery; * Patients treated with immunosuppressants and/or steroids in the past three months before surgery; * Patients in whom difficult airway is anticipated.
Where this trial is running
Belgrade
- Clinic for Vascular and Endovascular Surgery, University Clinical Center of Serbia — Belgrade, Serbia (Recruiting)
Study contacts
- Study coordinator: Igor Koncar, MD, Ph.D.
- Email: dr.koncar@gmail.com
- Phone: +381668300290
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.