CAPA in vitro egg maturation
Official title: CAPA In-vitro Oocyte Maturation
Run by Chinese University of Hong Kong · NCT06984081 · Data updated 2026-11-12
This trial will try the CAPA in vitro egg maturation technique for girls and women seeking fertility preservation or egg retrieval.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 0 Months to 50 Years |
| Sex | Women only |
| Enrollment | 100 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | November 10, 2025 |
| Main results expected | May 31, 2030 |
| Study ends | May 31, 2032 |
| Registry record updated | December 8, 2025 |
| Trial ID | NCT06984081 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are girls or women up to 50 years old who are seeking fertility preservation or oocyte retrieval, including those with polycystic ovaries or facing gonadotoxic treatment.
✕Probably not a fit
Patients who cannot provide consent or who have severe ovarian insufficiency unlikely to yield retrievable oocytes are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional program uses the CAPA in vitro oocyte maturation (IVM) method as a milder assisted reproductive approach compared with conventional ovarian stimulation. Eligible participants undergo oocyte retrieval followed by laboratory maturation with the CAPA protocol, aiming to produce mature eggs without full controlled ovarian stimulation. The approach may reduce cost and health risks for patients such as those with polycystic ovaries or women facing gonadotoxic chemotherapy. The program is offered at Prince of Wales Hospital under the sponsorship of the Chinese University of Hong Kong.
Why it matters
Potential benefit: If successful, CAPA IVM could provide a lower-cost, lower-risk way to obtain mature eggs for fertility preservation or conception.
How similar studies have gone: In vitro maturation has been used successfully in selected PCOS and fertility preservation settings, though CAPA-specific protocols are less widely tested and represent a refinement of existing IVM techniques.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged from 0-50 years old * Patients seek fertility preservation services * Patients seek oocyte retrieval services Exclusion Criteria: -Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)
Where it's running
-
Prince of Wales Hospital
Hong Kong, Hong Kong Recruiting
Study contacts
- Principal investigator: Pui Wah Jacqueline Chung — Chinese University of Hong Kong
- Study coordinator: Pui Wah Jacqueline Chung
- Email: jacquelinechung@cuhk.edu.hk
- Phone: +852 3505 1537
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.