CAPA in vitro egg maturation
CAPA In-vitro Oocyte Maturation
NA · Chinese University of Hong Kong · NCT06984081
This trial will try the CAPA in vitro egg maturation technique for girls and women seeking fertility preservation or egg retrieval.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 0 Months to 50 Years |
| Sex | Female |
| Sponsor | Chinese University of Hong Kong (other) |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT06984081 on ClinicalTrials.gov |
What this trial studies
This interventional program uses the CAPA in vitro oocyte maturation (IVM) method as a milder assisted reproductive approach compared with conventional ovarian stimulation. Eligible participants undergo oocyte retrieval followed by laboratory maturation with the CAPA protocol, aiming to produce mature eggs without full controlled ovarian stimulation. The approach may reduce cost and health risks for patients such as those with polycystic ovaries or women facing gonadotoxic chemotherapy. The program is offered at Prince of Wales Hospital under the sponsorship of the Chinese University of Hong Kong.
Who should consider this trial
Good fit: Ideal candidates are girls or women up to 50 years old who are seeking fertility preservation or oocyte retrieval, including those with polycystic ovaries or facing gonadotoxic treatment.
Not a fit: Patients who cannot provide consent or who have severe ovarian insufficiency unlikely to yield retrievable oocytes are unlikely to benefit.
Why it matters
Potential benefit: If successful, CAPA IVM could provide a lower-cost, lower-risk way to obtain mature eggs for fertility preservation or conception.
How similar studies have performed: In vitro maturation has been used successfully in selected PCOS and fertility preservation settings, though CAPA-specific protocols are less widely tested and represent a refinement of existing IVM techniques.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged from 0-50 years old * Patients seek fertility preservation services * Patients seek oocyte retrieval services Exclusion Criteria: -Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)
Where this trial is running
Hong Kong
- Prince of Wales Hospital — Hong Kong, Hong Kong (RECRUITING)
Study contacts
- Principal investigator: Pui Wah Jacqueline Chung — Chinese University of Hong Kong
- Study coordinator: Pui Wah Jacqueline Chung
- Email: jacquelinechung@cuhk.edu.hk
- Phone: +852 3505 1537
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Infertility, Female, In Vitro Oocyte Maturation Techniques