Clinical trial Recruiting at 1 site Interventional Ages 0 Months to 50 Women only

CAPA in vitro egg maturation

Official title: CAPA In-vitro Oocyte Maturation

Run by Chinese University of Hong Kong · NCT06984081 · Data updated 2026-11-12

This trial will try the CAPA in vitro egg maturation technique for girls and women seeking fertility preservation or egg retrieval.

Quick facts

Study typeInterventional
Ages0 Months to 50 Years
SexWomen only
Enrollment100 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedNovember 10, 2025
Main results expectedMay 31, 2030
Study endsMay 31, 2032
Registry record updatedDecember 8, 2025
Trial IDNCT06984081 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are girls or women up to 50 years old who are seeking fertility preservation or oocyte retrieval, including those with polycystic ovaries or facing gonadotoxic treatment.

Probably not a fit

Patients who cannot provide consent or who have severe ovarian insufficiency unlikely to yield retrievable oocytes are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional program uses the CAPA in vitro oocyte maturation (IVM) method as a milder assisted reproductive approach compared with conventional ovarian stimulation. Eligible participants undergo oocyte retrieval followed by laboratory maturation with the CAPA protocol, aiming to produce mature eggs without full controlled ovarian stimulation. The approach may reduce cost and health risks for patients such as those with polycystic ovaries or women facing gonadotoxic chemotherapy. The program is offered at Prince of Wales Hospital under the sponsorship of the Chinese University of Hong Kong.

Why it matters

Potential benefit: If successful, CAPA IVM could provide a lower-cost, lower-risk way to obtain mature eggs for fertility preservation or conception.

How similar studies have gone: In vitro maturation has been used successfully in selected PCOS and fertility preservation settings, though CAPA-specific protocols are less widely tested and represent a refinement of existing IVM techniques.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged from 0-50 years old
* Patients seek fertility preservation services
* Patients seek oocyte retrieval services

Exclusion Criteria:

-Patients unable to provide consent/assent (i.e. significant psychiatric problems/cognitive delay)

Where it's running

  • Prince of Wales Hospital
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.