Cannabidiol suppositories for sexual pain
Official title: The Use of Cannabidiol Suppositories for Sexual Pain: A Randomised Controlled Study
Run by London Metropolitan University · NCT07271030 · Data updated 2026-11-12
This project will test whether cannabidiol suppositories can reduce sexual pain and improve sexual function and well-being for adults who experience pain during intercourse or masturbation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | London Metropolitan University Academic / other |
| Locations | 1 site (London) |
| Status | Recruiting |
| Started | January 16, 2026 |
| Main results expected | July 2027 |
| Study ends | December 2027 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07271030 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 or older who are currently experiencing sexual pain, have previously used cannabidiol without allergic reaction, have tried intercourse in the past month, and screen in the mild range on PHQ-9 and GAD-7.
✕Probably not a fit
People with a history of allergic reaction to cannabidiol, moderate-to-severe depression or anxiety, co-occurring clinical difficulties, those under 18, or those not sexually active recently are unlikely to be eligible or benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults who report sexual pain are randomized to one of four groups: three cannabidiol suppository dose groups (about 30 mg, 50 mg, and 100 mg) or a care-as-usual control. The suppository intervention is used over one month with a planned follow-up visit at 12 weeks to measure pain, sexual function, quality of life, and well-being. The trial combines quantitative outcomes with qualitative feedback gathered via approximately eight open-ended questions. Participants must have prior cannabidiol use without allergy and meet mild screening thresholds for depression and anxiety to minimize confounding comorbidities.
Why it matters
Potential benefit: If successful, this could provide a non-intoxicating, locally delivered option to lessen sexual pain and improve sexual function, quality of life, and overall well-being.
How similar studies have gone: Two small prior studies of cannabidiol suppositories have suggested pain-relieving effects for sexual pain, but the evidence remains limited and preliminary.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Has previously used cannabidiol in any capacity and has not experienced any allergic reaction * Is experiencing sexual pain * There will be an absence of co occurring difficulties * Has attempted sexual intercourse in the last month * Age 18 years or older * Read and write English * Patient Health Questionnaire 9 screening score range between 0-9 mild * General Anxiety Disorder 7 screening score range between 0-9 mild * There are no restrictions on sex, gender, sexuality, or disability Exclusion Criteria: Has experienced an allergic reaction to cannabidiol in any capacity * Has not attempted sexual intercourse in the last month * Has co occurring difficulties * Aged below 18 years old * Are not experiencing sexual pain * Patient Health Questionnaire 9 screening score range between moderate to severe - 10-27 * General Anxiety Disorder 7 screening score range between 10- 21.
Where it's running
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School of Social Sciences and Professions
London, United Kingdom Recruiting
Study contacts
- Principal investigator: Samantha Banbury — London Metropolitan University
- Study coordinator: Anna Kamyk
- Email: rpo@londonmet.ac.uk
- Phone: 02074230000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.