Can blood inflammation markers predict a postdural puncture headache after cesarean section under spinal anesthesia?
Official title: The Effectiveness of Inflammatory Indices in Predicting Postdural Puncture Headache
Run by Amasya University · NCT07706751 · Data updated 2026-11-12
This study tests whether inflammation index values from routine blood tests can help predict which pregnant women having cesarean sections with spinal anesthesia might develop a postdural puncture headache.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | Women only |
| Enrollment | 260 (estimated) |
| Sponsor | Amasya University Academic / other |
| Locations | 1 site (Amasya) |
| Status | Recruiting |
| Started | June 15, 2026 |
| Main results expected | November 15, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT07706751 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women aged 18-45 undergoing elective cesarean section with spinal anesthesia at the participating center.
✕Probably not a fit
Patients who do not develop postdural puncture headache or whose inflammation markers do not correlate with risk may not benefit from the predictive approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, observational study will analyze pre- and post-operative blood test data from pregnant women undergoing elective cesarean sections with spinal anesthesia to see if inflammation indices can predict postdural puncture headache. It will also explore how factors like age, BMI, birth history, and other patient characteristics relate to the risk. The goal is to identify at-risk individuals so preventive measures can be considered. The research uses standard hemogram results and clinical data collected as part of routine care at Amasya University Hospital. No experimental interventions are described beyond observational data collection.
Why it matters
Potential benefit: If successful, the findings could enable earlier identification of patients at risk for postdural puncture headache and inform preventive or monitoring strategies.
How similar studies have gone: Prior research has explored inflammatory markers in perioperative settings, but this study applies a pregnancy-specific context to predict postdural puncture headache, making it relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * . Pregnant women who are of a cognitive level capable of giving informed consent * Pregnant women aged 18-45 who have undergone elective cesarean section * Term (37 weeks and above) pregnant women * Patients with an American Society of Anesthesiologists (ASA) physical status score of 2 (ASA II) Exclusion Criteria: * History of active infection or chronic inflammatory disease * History of steroid or immunomodulatory drug use * Presence of coagulopathy or hematological disorder * Presence of preeclampsia/HELLP syndrome * Those who received blood transfusions during and after surgery
Where it's running
-
Amasya University Training and Research Hospital
Amasya, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Osman O Kılınç, ass prof
- Email: zxgr03@gmail.com
- Phone: +905067352859
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.