Calf Muscle Pump Training vs. Unsupervised Home Walks for Venous Leg Ulcers
Official title: Optimizing Venous Leg Ulcer Healing Via Dose-Response Structured Calf Muscle Pump Activation Strategies Versus Unsupervised Home Walks
Run by MTI University · NCT07763782 · Data updated 2026-11-12
This study tests whether a structured, supervised calf muscle pump exercise program helps venous leg ulcers heal better than unsupervised home walking.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 60 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | MTI University Academic / other |
| Locations | 1 site (Amman) |
| Status | Recruiting |
| Started | October 1, 2026 |
| Main results expected | January 1, 2027 |
| Study ends | January 5, 2027 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07763782 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 20–60 with a confirmed non-healing venous leg ulcer (2–20 cm²) and ABI ≥ 0.8 who can consent and attend follow-ups.
✕Probably not a fit
Patients with recent DVT, severe heart failure, local infection or osteomyelitis, or conditions preventing ankle movement may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two approaches to boost blood flow and wound healing in venous leg ulcers: a dose‑response, structured calf muscle pump activation program delivered with supervision, and traditional advice to perform unsupervised home walks. Participants with non-healing venous ulcers are randomized to receive tailored exercise guidance or routine home walking, with outcomes including ulcer healing, adherence, vascular function, and quality of life. The study measures how frequency, duration, and intensity of calf exercises impact healing over time. Results could inform prescriptive activity guidelines to optimize treatment of leg ulcers.
Why it matters
Potential benefit: If successful, patients could experience faster ulcer healing and improved leg function through a more effective, structured exercise regimen.
How similar studies have gone: Previous research supports targeted exercise to improve venous return, but this specific dose‑response, supervised approach for venous ulcers is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria
* Age (ge 20 - 60) years with a confirmed, non-healing VLU (present for \\(\>6\\) weeks).
* Ulcer surface area between \\(2 \\text{ cm}\^2\\) and \\(20 \\text{ cm}\^2\\).
* Ankle-Brachial Index (ABI) \\(\\ge 0.8\\), ensuring adequate arterial perfusion.
* Able to provide informed consent and comply with follow-up appointments. Exclusion Criteria
* Severe, uncompensated congestive heart failure (NYHA Class III or IV).
* Active local wound infection or systemic osteomyelitis.
* Deep vein thrombosis (DVT) diagnosed within the past 3 months.
* Severe osteoarthritic limitations rendering ankle movement impossible.
Where it's running
-
Zaytoonah University
Amman, Jordan Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.