Calcitonin added to bupivacaine for transversalis fascia plane block during cesarean delivery
Official title: Analgesic Effect of Adding Calcitonin to Bupivacaine in Transversalis Fascia Plane Block for Cesarean Section, A Prospective Randomized Study
Run by Tanta University · NCT07033104 · Data updated 2026-11-12
This will see if adding calcitonin to bupivacaine in an ultrasound-guided transversalis fascia plane block gives better pain relief for women having cesarean delivery under spinal anesthesia.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | Women only |
| Enrollment | 70 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, Gharbia Governorate) |
| Status | Recruiting |
| Started | April 1, 2025 |
| Main results expected | August 1, 2025 |
| Study ends | September 1, 2025 |
| Registry record updated | June 24, 2025 |
| Trial ID | NCT07033104 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women classified as ASA II who are scheduled for cesarean section under spinal anesthesia at the study site and who consent to participate.
✕Probably not a fit
Patients undergoing emergency cesarean, those with significant pregnancy-related medical conditions, ASA >3, coagulopathy, or those who refuse participation are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants at Tanta University Hospital will receive an ultrasound-guided transversalis fascia plane block with bupivacaine, with some patients also receiving calcitonin as an added adjuvant. The trial compares postoperative analgesia measures such as pain scores, duration of analgesia, and opioid consumption between groups. Eligible patients are women classified as ASA II scheduled for cesarean section under spinal anesthesia; exclusions include patient refusal, ASA >3, emergency cesarean section, pregnancy-related medical complications, or coagulopathy. The study is a single-center intervention using standard ultrasound-guided injection techniques performed by anesthesiology staff.
Why it matters
Potential benefit: If successful, adding calcitonin could prolong the block and reduce postoperative opioid needs after cesarean delivery.
How similar studies have gone: Using calcitonin as an adjuvant for peripheral nerve or fascial plane blocks is relatively novel with limited prior published evidence compared with more commonly used adjuvants.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * female pt ASA2 scheduled for cs under spinal anesthesia Exclusion Criteria: * patient refusal ASAmore than 3 patients with pregnancy related disease emergency cs history of coagulopathy
Where it's running
-
tanta University hospital
Tanta, Gharbia Governorate, Egypt Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Analgesia after open inguinal hernia repair using intrathecal morphine or a transversalis fascia plane block
This trial tests whether intrathecal morphine or a ultrasound-guided transversalis fascia plane block can provide better pain relief after open inguinal hernia repair in adults.
-
Transversalis fascia plane block versus intrathecal dexmedetomidine for pain after cesarean section
This will try whether an ultrasound-guided transversalis fascia plane (TFP) nerve block or injecting dexmedetomidine into the spinal fluid gives better pain relief for women having a cesarean under spinal anesthesia.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.