Calcitonin added to bupivacaine for transversalis fascia plane block during cesarean delivery
Analgesic Effect of Adding Calcitonin to Bupivacaine in Transversalis Fascia Plane Block for Cesarean Section, A Prospective Randomized Study
This will see if adding calcitonin to bupivacaine in an ultrasound-guided transversalis fascia plane block gives better pain relief for women having cesarean delivery under spinal anesthesia.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Sex | Female |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta, Gharbia Governorate) |
| Trial ID | NCT07033104 on ClinicalTrials.gov |
What this trial studies
Participants at Tanta University Hospital will receive an ultrasound-guided transversalis fascia plane block with bupivacaine, with some patients also receiving calcitonin as an added adjuvant. The trial compares postoperative analgesia measures such as pain scores, duration of analgesia, and opioid consumption between groups. Eligible patients are women classified as ASA II scheduled for cesarean section under spinal anesthesia; exclusions include patient refusal, ASA >3, emergency cesarean section, pregnancy-related medical complications, or coagulopathy. The study is a single-center intervention using standard ultrasound-guided injection techniques performed by anesthesiology staff.
Who should consider this trial
Good fit: Women classified as ASA II who are scheduled for cesarean section under spinal anesthesia at the study site and who consent to participate.
Not a fit: Patients undergoing emergency cesarean, those with significant pregnancy-related medical conditions, ASA >3, coagulopathy, or those who refuse participation are excluded and unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, adding calcitonin could prolong the block and reduce postoperative opioid needs after cesarean delivery.
How similar studies have performed: Using calcitonin as an adjuvant for peripheral nerve or fascial plane blocks is relatively novel with limited prior published evidence compared with more commonly used adjuvants.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * female pt ASA2 scheduled for cs under spinal anesthesia Exclusion Criteria: * patient refusal ASAmore than 3 patients with pregnancy related disease emergency cs history of coagulopathy
Where this trial is running
Tanta, Gharbia Governorate
- tanta University hospital — Tanta, Gharbia Governorate, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.