Calamansi capsules to see if they change blood sugar and insulin in healthy young adults
Official title: The Effects of Calamansi (Citrus x Macrocarpa Bunge) Supplementation on Blood Glucose and Insulin Levels in Healthy Volunteers
Run by Burapha University · NCT07587905 · Data updated 2026-11-12
This study tests whether calamansi capsules can affect blood glucose and insulin levels in healthy 18–30-year-olds compared with a placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 30 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Burapha University Academic / other |
| Locations | 1 site (Mueang, Burapha University) |
| Status | Recruiting |
| Started | May 1, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | January 31, 2027 |
| Registry record updated | May 15, 2026 |
| Trial ID | NCT07587905 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy 18–30-year-olds with BMI 18.5–22.9 kg/m² and no history of diabetes or liver/pancreatic disease.
✕Probably not a fit
Individuals with citrus allergies, those on medications affecting glucose metabolism, or with conditions that alter blood sugar may not benefit or could be excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Fifty-four healthy, sedentary adults aged 18–30 will be randomly assigned to receive either calamansi powder capsules or placebo capsules for 12 weeks. The study will measure fasting glucose, insulin, creatinine, ALT, and MDA at baseline, after a single dose, and after 12 weeks. Health screenings and vital signs will be collected, and body composition will be assessed to ensure eligibility. The trial uses a controlled, parallel design to compare changes between groups over time.
Why it matters
Potential benefit: If successful, calamansi capsules could offer a simple dietary supplement to support glucose and insulin control in young adults.
How similar studies have gone: Previous studies on citrus-derived compounds have shown mixed results; this trial explores a specific calamansi preparation in a healthy population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy individuals who have not been diagnosed with diabetes or prediabetes, with a fasting blood glucose level (after 8 hours of fasting) of less than 100 mg/dL. * Aged between 18-30 years, both male and female * Body Mass Index (BMI) between 18.5 and 22.9 kg/m² * No diseases affecting blood sugar levels, such as liver or pancreatic diseases Exclusion Criteria: * Pregnant or breastfeeding women * Regular smokers * Regular alcohol consumers * Individuals with a history of allergies to citrus fruits or citrus-derived ingredients * Individuals taking medications that affect glucose metabolism and fat distribution in the body, including steroids, protease inhibitors, and psychiatric medications. These refer to drugs that act on the central nervous system and may affect blood sugar levels or energy metabolism, such as antidepressants, antipsychotics, and mood stabilizers.
Where it's running
-
Piyapong Prasertsri
Mueang, Burapha University, Thailand Recruiting
Study contacts
- Principal investigator: Piyapong Prasertsri, Ph.D. — Faculty of Allied Health Sciences, Burapha University
- Study coordinator: Piyapong Prasertsri, Ph.D.
- Email: piyapong@buu.ac.th
- Phone: 6638103166
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.