Bump the Lump: a speech-language therapy program for persistent throat lump sensations
Official title: Bump the Lump: Creation and Validation of Speech Language Pathology Intervention for the Treatment of Globus Pharyngeus
Run by Wake Forest University Health Sciences · NCT06762444 · Data updated 2026-11-12
This project will try a standardized speech-language therapy program to see if it reduces the persistent lump or tightness in the throat in adults with globus pharyngeus.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | Wake Forest University Health Sciences Academic / other |
| Locations | 1 site (Winston-Salem, North Carolina) |
| Status | Recruiting |
| Started | August 28, 2025 |
| Main results expected | August 2027 |
| Study ends | August 2027 |
| Registry record updated | August 28, 2026 |
| Trial ID | NCT06762444 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age 18 and over) seen at the Atrium Health Wake Forest Baptist Center for Voice and Swallowing Disorders who report a complaint of globus pharyngeus and do not have a diagnosed swallowing disorder.
✕Probably not a fit
Patients with diagnosed swallowing disorders, or whose throat symptoms are clearly caused by dysphagia, gastroesophageal reflux, or major esophageal motor disorders, are unlikely to benefit from this behavioral SLP protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a proof-of-concept intervention that develops and delivers a standardized speech-language pathology (SLP) protocol for adults reporting globus pharyngeus. Participants evaluated at the Atrium Health Wake Forest Baptist Center for Voice and Swallowing Disorders will receive the SLP protocol while patients with swallowing disorders are excluded. The study addresses a gap in the literature where existing SLP approaches for globus are heterogeneous and not consistently applied. Symptom response and patient-reported impact on quality of life will be tracked to determine whether a standardized approach is practical and helpful.
Why it matters
Potential benefit: If successful, the protocol could reduce throat lump symptoms and improve quality of life by providing a consistent, repeatable SLP treatment approach.
How similar studies have gone: Previous SLP interventions for globus have shown some promise but results are mixed and methods vary widely, so benefit remains uncertain without a standardized protocol.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Volunteer adult patients (age 18 and over) evaluated at the Atrium Health Wake Forest Baptist Center for Voice and Swallowing Disorders who report a complaint of globus pharyngeus Exclusion Criteria: * Patients diagnosed with a swallowing disorder will be excluded from the study
Where it's running
-
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States Recruiting
Study contacts
- Principal investigator: Lyndsay Madden, DO — Wake Forest University Health Sciences
- Study coordinator: Lyndsay Madden, DO
- Email: lmadden@wakehealth.edu
- Phone: (336) 716-4161
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.