Building a cohort for monitoring patients using ovarian tissue autografts
Constitution of a Cohort for Monitoring Patients Candidating for Ovarian Tissue Autograft
Centre Hospitalier Universitaire de Besancon · NCT02855827
This study is trying to see how well ovarian tissue grafts work for women who have had their ovarian tissue frozen and want to restore their ovarian function.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 240 (estimated) |
| Ages | 11 Years to 43 Years |
| Sex | Female |
| Sponsor | Centre Hospitalier Universitaire de Besancon (other) |
| Locations | 1 site (Besançon) |
| Trial ID | NCT02855827 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to establish a cohort of patients who have undergone ovarian cryopreservation and may benefit from autografting their ovarian tissue. The study will follow these patients to evaluate their requests for ovarian tissue grafting, assess the effectiveness of the autograft technique, and monitor any residual disease risks. The cohort will also facilitate the restoration of ovarian function in eligible patients, particularly those with premature ovarian insufficiency. This observational study will provide valuable insights into the outcomes of ovarian tissue autografts.
Who should consider this trial
Good fit: Ideal candidates include patients aged 11 to 43 years who have cryopreserved their ovarian tissue and have premature ovarian insufficiency.
Not a fit: Patients under 11 years or over 43 years, as well as those who refuse participation, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance fertility preservation options for patients with ovarian function insufficiency.
How similar studies have performed: Other studies have shown promising results with ovarian tissue autografting, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have cryopreserved their ovarian tissue; * Patients with premature ovarian insufficiency; * Patients older than 11 years (bone age) for induction of puberty; * Patients aged from 18 to 43 years for the restoration of ovarian function; * No objection from the patient * Patients who have already received ovarian tissue autograft. Exclusion Criteria: * Patients aged under 11 years (bone age); * Patients older than 43 years; * Patients refusing to be included; * Patients (adults) under guardianship, curators and safeguard justice
Where this trial is running
Besançon
- CHRU Besancon — Besançon, France (RECRUITING)
Study contacts
- Study coordinator: Chlotilde AMIOT, MD, PhD
- Email: camiot@chu-besancon.fr
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ovarian Function Insufficiency