Clinical trial Recruiting at 1 site Interventional Ages 20 to 60

Buccal nerve trunk versus conventional buccal nerve injection for lower molar extraction

Official title: Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block for Anaesthesia of Buccal Mucosa During Extraction of Mandibular Posterior Teeth

Run by Watim Medical & Dental College · NCT07330518 · Data updated 2026-11-12

This trial will try whether a buccal nerve trunk block or the conventional buccal nerve block gives better pain control and reduces extra injections for adults having lower molar extractions.

Quick facts

Study typeInterventional
Ages20 Years to 60 Years
SexAll
Enrollment100 (estimated)
SponsorWatim Medical & Dental College
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Islamabad, Islamabad, Pakistan)
StatusRecruiting
StartedMarch 20, 2026
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedFebruary 4, 2026
Trial IDNCT07330518 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 20–60 of either sex who require extraction of mandibular molars and do not have exclusions such as pregnancy, associated tooth pathology, ongoing radiotherapy/chemotherapy, or mandibular fracture.

Probably not a fit

Patients who are pregnant, have tooth-related pathologies (cysts or tumors), are receiving radiotherapy or chemotherapy, have a mandibular fracture, or are outside the 20–60 age range are unlikely to be eligible or to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized interventional trial compares the conventional buccal nerve block with a buccal nerve trunk block for anesthesia of the buccal mucosa during extraction of mandibular molars. Pain will be measured with a visual analogue scale (VAS) during both the injection and the extraction, with VAS scores over 4 labelled as positive pain perception. Need for supplemental infiltration is defined as use of more than one anesthesia cartridge and will be recorded as a primary outcome alongside intraoperative pain. The trial is conducted at a single center and enrolls adults aged 20–60 undergoing mandibular molar extraction.

Why it matters

Potential benefit: If successful, the buccal nerve trunk block could reduce pain during injection and extraction and lower the need for additional anesthesia injections.

How similar studies have gone: Smaller clinical and anatomical reports suggest the buccal nerve trunk block can improve buccal mucosa anesthesia compared with conventional techniques, but high-quality randomized data are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 20 to 60 years
* Patients of both gender
* Patient requiring extraction of mandibular molars

Exclusion Criteria:

* Pregnant women
* Pathologies associated with teeth i.e. cysts, tumors
* Patients on radiotherapy or chemotherapy
* Patients with mandibular fracture

Where it's running

  • Watim Medical College & Dental Hospital
    Islamabad, Islamabad, Pakistan, Pakistan
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.