Bright light therapy for improving symptoms in Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial aims to investigate the effects of bright light therapy on motor symptoms and sleep disorders in patients with Parkinson's disease. The study involves administering bright light exposure of 4000 to 6000 lux for 60 minutes before bedtime to assess improvements in mood, anxiety, and motor function. Previous open studies have shown promising results, but this trial seeks to confirm these findings specifically in Chinese patients with Parkinson's disease. The research will also explore the underlying mechanisms of how light therapy may benefit these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* According to the criteria of PD diagnosis of the MDS, PD patients were selected as the research object. The clinical symptoms of PD patients were consistent with Hoehn and Yahr stages 2-3.
* All PD patients have maintained stable drug treatment for at least one month, signed clinical informed consent and agreed not to adjust drugs throughout the light test and follow-up period.

Exclusion Criteria:

* Using hypnotic or stimulating drugs.
* Using antidepressants, except stable drugs maintained for more than three months;
* Visual impairment, such as cataract, glaucoma, blindness, etc;
* Cognitive impairment (MMSE \< 24);
* There are uncontrollable hallucinations and mental diseases;
* There are sleep phase delay / advance syndrome, shift work, jet lag, etc

Where it's running

• Department of Neurology, Second Affiliated Hospital of Soochow University
  Suzhou, Jiangsu, China Recruiting

Study contacts

• Principal investigator: Chun-Feng Liu, PhD — Second Affiliated Hospital of Soochow University
• Study coordinator: Chun-Feng Liu, PhD
• Email: liuchunfeng@suda.edu.cn
• Phone: +86 512 67783307

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.