Breathing training program for improving exercise capacity in patients with non-cystic fibrosis bronchiectasis
Home-based, Digitally Delivered Breathing Training in People With Non-cystic Fibrosis Bronchiectasis: A Randomized Control Trial
This study is testing if a home breathing training program can help people with non-cystic fibrosis bronchiectasis exercise better and improve their lung function.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 21 Years to 80 Years |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Jacksonville, Florida) |
| Trial ID | NCT05860803 on ClinicalTrials.gov |
What this trial studies
This research investigates the effects of a home-based breathing and respiratory muscle training program, supported by a health coach, on exercise capacity and lung function in individuals diagnosed with non-cystic fibrosis bronchiectasis. Participants will engage in a structured regimen using LungTrainers to enhance their respiratory muscles and overall clinical status. The study aims to determine if this intervention can lead to significant improvements in the ability to exercise and quality of life for these patients.
Who should consider this trial
Good fit: Ideal candidates are patients with a confirmed diagnosis of non-cystic fibrosis bronchiectasis who are clinically stable and able to provide informed consent.
Not a fit: Patients with significant coexisting diseases, advanced heart failure, or recent acute exacerbations may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly enhance exercise capacity and lung function for patients with non-cystic fibrosis bronchiectasis.
How similar studies have performed: Other studies have shown promising results with similar breathing training approaches, indicating potential for success in this intervention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks. * Able and willing to provide informed consent to participate in the study. Exclusion Criteria: * Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise. * Presence of advanced heart failure. * Current use of antibiotics. * Acute exacerbation(s) within 3-weeks prior to study commencement. * Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.
Where this trial is running
Jacksonville, Florida
- Mayo Clinic Florida — Jacksonville, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Bryan Taylor, PhD — Mayo Clinic
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.