Breast biomechanics and bra support after surgery and radiotherapy.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers at Portsmouth Hospitals and the University of Portsmouth will recruit women treated for unilateral breast cancer from Queen Alexandra Hospital and invite them to the University of Portsmouth biomechanics lab for testing after surgery and/or after radiotherapy, with an optional pre-surgery visit. The protocol uses 3D surface scans and wearable sensors to quantify breast shape and movement, comparing the treated breast to the contralateral breast as an internal control. Participants will complete short questionnaires about their bra requirements, exercise habits, and their experience of the testing procedures. The study excludes people with metastatic or bilateral disease, recent surgery or radiotherapy within the exclusion windows, active postoperative infection or dressings, pregnancy or breastfeeding, epilepsy, high frailty, or those requiring an interpreter.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female
* 18 years of age or above
* Early or locally advanced breast cancer classified as B5a or B5b (radical treatment intent)
* Unilateral breast cancer (contralateral breast used as control)
* Receiving or has received breast cancer surgery
* +/- Adjuvant radiotherapy
* Able to travel to the University of Portsmouth Breast biomechanics laboratory
* Participant has capacity to consent.

Exclusion Criteria:

* Metastatic breast cancer diagnosis
* \< 2 weeks post-operative
* \< 4 weeks post-radiotherapy
* Active post-operative breast infection
* Requirement of ongoing breast dressings
* Previous breast surgery to contralateral breast
* Bilateral breast cancer
* Epilepsy (due to strobe on 3D scanner)
* Pregnancy or \<6 weeks post-partum
* Breastfeeding
* Rockwood Frailty score \>5 (or those unable to ambulate un-aided)
* Requiring interpreter.

Where it's running

• Queen Alexandra Hospital
  Portsmouth, United Kingdom Recruiting

Study contacts

• Principal investigator: Edward St John — Portsmouth Hospitals NHS Trust
• Study coordinator: Amy Huseyin
• Email: Amyrose.Huseyin@porthosp.nhs.uk
• Phone: 02392 286000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Post-treatment care program for breast and prostate cancer survivors

  This program tests whether a focused questionnaire plus quality-of-life screening can detect and help manage side effects in people who have finished curative treatment for breast or prostate cancer.

  Recruiting Masaryk Memorial Cancer Institute · Brno · NCT07253987

• One-stage prepectoral implant versus two-stage expander-to-implant breast reconstruction after mastectomy and radiotherapy

  This compares immediate one-stage prepectoral implant reconstruction with two-stage expander-to-implant reconstruction in women who will have radiotherapy after mastectomy to see if one approach gives better quality of life and fewer complications.

  Recruiting Henan Cancer Hospital · Henan, Henan · NCT07037576

• Laparoscopic nipple- and areola-sparing mastectomy with immediate implant, patch, and fat grafting reconstruction

  This will test whether laparoscopic nipple- and areola-sparing mastectomy with an immediate pectoral-muscle implant plus patch and same-time autologous fat grafting is safe and effective for women with early unilateral breast cancer (cT1-2N0M0).

  Recruiting Henan Cancer Hospital · Zhengzhou, Henan · NCT07037537

• Cold salt-water foot baths to prevent paclitaxel-related nerve damage

  This study tests whether taking cold salt-water or plain cold-water foot baths during paclitaxel chemotherapy can prevent or reduce chemotherapy-related peripheral nerve damage in women with breast cancer.

  Recruiting Istanbul Topkapi University · Istanbul, Uskudar · NCT06964802

• Comparing two pain management techniques for breast cancer surgery

  This study is testing whether a new pain management technique called erector spinae plane block can help people recovering from breast cancer surgery feel less pain and use fewer opioids compared to the traditional epidural method.

  Recruiting National Cancer Institute, Egypt · Cairo · NCT06884852

• Sensorimotor training for breast cancer patients with chemotherapy-induced peripheral neuropathy

  This study tests if sensorimotor training can help breast cancer patients with nerve pain from chemotherapy feel better and improve their balance and exercise ability.

  Recruiting at 2 sites Riphah International University · Lahore, Punjab Province and 1 other locations · NCT06737926

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.