Braun junction after pancreatic surgery to see if it helps stomach emptying

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores whether Braun enteroenterostomy added to the standard Billroth II reconstruction after pancreaticoduodenectomy reduces postoperative delayed gastric emptying. Eligible adults with malignant or borderline periampullary tumors undergoing curative PD are enrolled and randomized to receive Braun anastomosis with the standard reconstruction. The trial aims to see if this adjustment lowers DGE incidence, improves oral intake, shortens hospital stay, and supports earlier recovery. Outcomes focus on postoperative gastric emptying, complication rates, and recovery milestones in the early postoperative period. The study addresses ongoing questions about the effectiveness of Braun anastomosis in this surgical context.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years, male or female;
* Scheduled to undergo curative pancreaticoduodenectomy (PD);
* Undergoing PD for malignant or borderline tumors, with planned antecolic Billroth II reconstruction;
* Mentally competent and able to provide written informed consent.

Exclusion Criteria:

* Age \< 18 years;
* Prior diagnosis of gastroparesis;
* Benign disease as the indication for PD;
* Previous history of upper gastrointestinal surgery;
* Preoperative pyloric obstruction;
* Planned pylorus-preserving pancreaticoduodenectomy (PPPD);
* Patients who have received neoadjuvant or conversion therapy;
* Preoperative glycated hemoglobin (HbA1c) \> 7.5%;
* Preoperative total bilirubin level \> 200 μmol/L;
* Unable or unwilling to provide written informed consent.

Where it's running

• Tianjin Medical University Cancer Institute & Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Yunlong Cui, PhD
• Email: ningyunlong@163.com
• Phone: +86 18622228633

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.