Brain–spinal cord–muscle connectivity during selective dorsal rhizotomy in children with spasticity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project uses intraoperative neuroelectrophysiological monitoring to capture cortico-medullo-radiculo-muscular signals that have not previously been recorded during selective dorsal rhizotomy. Participants are children aged 3–17 scheduled for the standard surgical procedure, and the recordings are taken during the operation without altering clinical care. The goal is to map variations in neural connectivity and relate those patterns to clinical presentation to inform refinements of the surgical technique. The work is being conducted at pediatric and neurosurgical centers in Nice and Paris.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients aged 3 to 17 years included
* scheduled for selective rhizotomy surgery
* Having received informed consent to participate in the study (written consent from both parents)
* Affiliated or beneficiary of a social security scheme

Exclusion Criteria:

* Contraindications to selective rhizotomy
* History of epilepsy
* Known neurological and/or psychiatric disorders with past and/or current medical treatment, or drug addiction
* Patient under legal protection
* Pregnant or breast-feeding women

Where it's running

• Hpu Lenval
  Nice, France Recruiting
• Hfar
  Paris, France Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.