Clinical trial Recruiting at 1 site Observational Ages 20 to 80

Brain activity while walking after stroke

Official title: Cortical Activation During Forward and Backward Walking in Individuals With Chronic Stroke

Run by National Yang Ming Chiao Tung University · NCT06840405 · Data updated 2026-11-12

This project will record brain activity while people who had a stroke walk forward and backward to see how the two sides of the brain balance during walking.

Quick facts

Study typeObservational
Ages20 Years to 80 Years
SexAll
Enrollment30 (estimated)
SponsorNational Yang Ming Chiao Tung University
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedApril 24, 2025
Main results expectedDecember 30, 2027
Study endsFebruary 28, 2028
Registry record updatedJune 12, 2025
Trial IDNCT06840405 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are people at least six months after stroke who can walk independently for at least 7 meters and have an MMSE score of 24 or higher.

Probably not a fit

People who cannot walk backward, have neuromuscular disorders, visual or auditory impairments, unstable cardiac status or uncontrolled hypertension, or musculoskeletal problems affecting walking would be excluded and unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will record noninvasive measures of cortical activity while participants with chronic stroke perform forward and backward walking tasks. Eligible participants are at least six months post-stroke, can walk independently for at least 7 meters, and have preserved cognition (MMSE ≥ 24). The protocol compares activation in the affected and unaffected hemispheres during walking to characterize interhemispheric balance. Findings aim to map gait-related cortical activation patterns to inform rehabilitation strategies.

Why it matters

Potential benefit: If successful, the findings could help therapists target rehabilitation to rebalance brain activity and improve walking after stroke.

How similar studies have gone: Previous work has shown that treadmill training and other gait interventions can change motor cortex excitability after stroke, so this observational work builds on prior findings.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥ 6 months after the diagnosis of stroke
* Independent walking over at least 7m with or without a walking aid
* Mini-mental state examination score ≥ 24

Exclusion Criteria:

* Had difficulty in backward walking
* Any neuromuscular disorders history
* With visual or auditory disorders
* Unstable cardiac status or uncontrolled hypertension
* Any musculoskeletal disorders that would affect walking ability

Where it's running

  • Department of Physical Therapy and Assistive Technology, National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.