Botulinum toxin injections after laparoscopic colectomy to help wound healing
Official title: Efficacy and Safety of Botulinum Toxin Type A Injection for Surgical Wound Healing in Patients Undergoing Laparoscopic Colectomy at Thong Nhat Hospital, Ho Chi Minh City
Run by Pham Ngoc Thach University of Medicine · NCT07795463 · Data updated 2026-11-12
This study tests whether injecting botulinum toxin type A around the surgical scar after laparoscopic colectomy helps wounds heal better than standard care in adults in Vietnam.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Pham Ngoc Thach University of Medicine Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Ho Chi Minh City) |
| Status | Recruiting |
| Started | August 10, 2026 |
| Main results expected | October 31, 2026 |
| Study ends | October 31, 2026 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT07795463 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) of Vietnamese nationality undergoing laparoscopic colectomy who can provide informed consent and attend follow-up.
✕Probably not a fit
Patients with contraindications to botulinum toxin or who do not receive the injection may not experience any additional benefit beyond standard care.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial compares intradermal botulinum toxin type A injections given along the incision after laparoscopic colectomy to routine postoperative wound care. Participants are adults undergoing the procedure and are randomly assigned to receive the BTX-A injection or not, with follow-up to assess wound healing, scar appearance, and safety. The study is conducted at Thong Nhat Hospital in Ho Chi Minh City, Vietnam, with informed consent required. Primary outcomes focus on wound healing and scar quality, while adverse events related to BTX-A are monitored throughout follow-up.
Why it matters
Potential benefit: If successful, BTX-A injections could improve wound healing and cosmetic scar outcomes after laparoscopic colectomy.
How similar studies have gone: Previous similar approaches in surgical wound care have shown mixed results; this study explores efficacy in a specific abdominal procedure context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years or older. * Vietnamese nationality. * Indication for laparoscopic colectomy. * Willing and able to provide written informed consent to participate in the study. Exclusion Criteria: * Pregnancy or breastfeeding. * History of allergy to botulinum toxin type A. * History of botulinum toxin type A injection at or near the surgical site within the previous 6 months. * History of radiotherapy, chemotherapy, hematologic disorders, psychiatric disorders, or myasthenia gravis. * Unstable chronic diseases, including uncontrolled hypertension or diabetes mellitus. * Unable to attend scheduled follow-up visits.
Where it's running
-
Thong Nhat hospital
Ho Chi Minh City, Vietnam Recruiting
Study contacts
- Study coordinator: To Trinh Ngoc Chau, MSc
- Email: bstrinh86@gmail.com
- Phone: +84937262323
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.