Boswellia serrata for pain sensitivity and pain modulation in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, placebo-controlled crossover study in healthy volunteers comparing Boswellia serrata extract with placebo. Participants will undergo quantitative sensory testing (QST) to measure peripheral and central sensitization and descending pain inhibitory pathways before and after each treatment period. The study uses well-defined exclusion criteria to avoid confounding by chronic pain, medications, or major medical conditions. Results aim to clarify whether observed clinical analgesic effects of Boswellia are linked to changes in pain processing mechanisms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: ≥18 years

Exclusion Criteria:

* Not pregnant or breastfeeding
* No renal or liver insufficiency
* No neurological/dermatological/cardiovascular diseases
* No chronic pain and/or use of analgesics
* No use of anticoagulants
* No use of antidepressants
* No use of MAO inhibitors
* No use of St. John's Wort
* No use of medications affecting the CYP mechanism
* No allergies to Boswellia serrata or capsaicin"

Where it's running

• Medical University of Graz
  Graz, Styria, Austria Recruiting

Study contacts

• Study coordinator: Helmar Bornemann-Cimenti, PD Dr. MD MSc MBA
• Email: helmar.bornemann@medunigraz.at
• Phone: +43 316 385 81103

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.