Bone scintigraphy to find cervical pseudarthrosis
Official title: Diagnostic Interest of Bone Tomoscintigraphy in the Search for Cervical Pseudarthrosis
Run by GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT07140432 · Data updated 2026-11-12
This trial will test whether bone scintigraphy can help detect cervical pseudarthrosis in adults who had prior cervical fusion and still have neck symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 99 Years |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | GCS Ramsay Santé pour l'Enseignement et la Recherche Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Bourg-en-Bresse) |
| Status | Recruiting |
| Started | December 31, 2024 |
| Main results expected | February 28, 2027 |
| Study ends | February 28, 2027 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT07140432 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 21 who had cervical fusion, are followed at the participating clinics, have an NDI greater than 5 at one year post‑op, and have social security coverage are the intended participants.
✕Probably not a fit
Patients needing urgent treatment, pregnant or breastfeeding individuals, those under legal protection, or anyone with known hypersensitivity to sodium oxidronate will not be eligible and are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial enrolls adults over 21 who previously underwent cervical arthrodesis and have persistent symptoms with an NDI score greater than 5 about one year after surgery. Participants will undergo bone scintigraphy with sodium oxidronate in addition to standard imaging such as CT to look for functional signs of nonunion. The aim is to determine whether functional bone imaging provides information about the nature of bone bridges and incomplete consolidation that CT morphology alone does not capture. Imaging findings will be compared with clinical signs and existing radiologic data to inform diagnostic accuracy and potential need for revision surgery.
Why it matters
Potential benefit: If successful, bone scintigraphy could improve detection of cervical nonunion and help target revision surgery to patients who truly need it.
How similar studies have gone: Functional bone scintigraphy has shown promise in spine fusion contexts but has limited high‑quality validation specifically for cervical pseudarthrosis, while CT remains the morphological gold standard.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 21 years of age * Patients who have undergone cervical arthrodesis and are being treated at Clinique de la Sauvegarde or Clinique Convert * Patients with a NDI clinical score at 1 year greater than 5 * Patient affiliated to/ or beneficiary of a Social Security scheme as definied by the law Exclusion Criteria: * Patients whose clinical condition requires rapid treatment that can't wait for examinations to be carried out * Pregnancy and breastfeeding * Protected person (curatorship, guardianship, safeguard of justice) * History of hypersensitivity to the active substance ( sodium oxidronate) or to any of its constituents
Where it's running
-
Clinique Convert ( INA)
Bourg-en-Bresse, France Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.