Blue light to speed healing of donor-site wounds after skin grafts

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with intermediate-to-deep burns who require split-thickness skin grafting and have at least two donor sites will receive standard care on one donor area and standard care plus blue light photobiomodulation on another, allowing within-patient comparison. Investigators will measure time to re-epithelialization, wound condition, pain scores, signs of infection, safety and tolerability, and longer-term scar quality. The intervention consists of noninvasive blue light applied in addition to routine postoperative dressings over the donor-site healing period. The trial is conducted at the burn center of Osp. Maurizio Bufalini in Cesena, Italy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with intermediate-deep burns with Total Body Surface Area (TBSA) \> 10% requiring surgical treatment with escharectomy, presenting at least two Donor Site.
* Patients over 18 years of age;
* Patients who have signed the informed Consent Form (ICF) and understood the purpose of the study, or, if unable to give consent personally due to their condition, their legal guardian.

Exclusion Criteria:

* Intermediate-deep burns TBSA \< 10% or superficial burns;
* Patients under the age of 18;
* Patients who are participating in other clinical trials with drugs or medical devices;
* Patients with neoplasms or other conditions requiring the use of cytostatic or immunosuppressive drugs;
* Patients with conditions that induce skin photosensitivity;
* Pregnant or breastfeeding women;
* Patients or relatives who are unable to understand the purposes of the trial;

Where it's running

• U.O. Centro Grandi Ustionati - Osp. Maurizio Bufalini
  Cesena, Forlì-Cesena, Italy Recruiting

Study contacts

• Study coordinator: Jutta Renate Lehmann, Dr.
• Email: juttarenate.lehmann@auslromagna.it
• Phone: +39 3391023866

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Impact of inspiratory muscle training after burn injury

  This study tests whether inspiratory muscle training helps people who have had burn injuries and inhalation damage improve breathing and physical function.

  Recruiting Cairo University · Giza · NCT07867639

• Donor ankle sensorimotor recovery after ACL reconstruction with a peroneus longus graft

  This study tests how the donor ankle recovers sensorimotor function after ACL reconstruction using a peroneus longus tendon autograft in adults 18–55.

  Recruiting Gazi University · Çankaya, Ankara · NCT07762989

• Nano-biofusion gingival gel to improve palate wound healing after gum grafts

  We will try a nano-biofusion gingival gel (NBF) to see if it speeds healing, reduces pain, and lowers inflammation for adults who have a palatal donor wound after soft tissue gum graft surgery.

  Recruiting King Abdullah University Hospital · Irbid, Irbid Governorate · NCT07330154

• VR-enhanced progressive muscle relaxation for chronic symptoms after burn injury

  This will try progressive muscle relaxation with and without virtual reality to see if it helps adult burn survivors reduce chronic pain, itch, anxiety, sleep problems, or fatigue.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07317271

• Lateral, Anterior, Medial (LAM) femoral cutaneous block for thigh donor-site pain

  This tries to see if a LAM nerve block can numb the anterolateral thigh and reduce donor-site pain without weakening leg muscles in adults having split-thickness skin grafts.

  Recruiting University of Washington · Seattle, Washington · NCT07221903

• Aloe vera gel versus paraffin tulle dressings for donor-site pain after split-thickness skin grafts

  This trial tests whether Aloe vera gel dressings reduce pain more than paraffin tulle dressings for adults (18–60) after split-thickness skin graft donor-site wounds.

  Recruiting King Edward Medical University · Lahore, Punjab Province · NCT07057557

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.