Blood p‑Tau217 test to help diagnose Alzheimer's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will recruit 150 patients at the CHU Amiens memory center over an 18‑month period who are already scheduled for lumbar puncture because of suspected Alzheimer's disease. During the same hospitalization when CSF is collected for standard biomarkers, a single EDTA blood tube will be taken to measure plasma p‑Tau217. Plasma p‑Tau217 performance will be compared with established CSF biomarkers (Aβ1‑40, Aβ1‑42, total tau, p‑Tau181) and with the clinical diagnosis of AD. Analyses will report diagnostic accuracy measures and concordance between plasma and CSF results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients addressed to the memory center of CHU Amiens with a clinical suspicion of AD, for whom lumbar puncture / CSF biomarkers of AD determination is proposed.

Exclusion Criteria:

* Minor patients
* pregnant women
* patients under guardianship

Where it's running

• CHRU Amiens
  Amiens, France Recruiting

Study contacts

• Study coordinator: Pia-Manuela Rusu, MD
• Email: rusu.pia-manuela@chu-amiens.fr
• Phone: 33+322087015

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.