Blood markers to detect infected pancreatic necrosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study enrolling adults with necrotizing pancreatitis confirmed by contrast-enhanced CT. Investigators will collect blood samples and clinical data over the course of care to look for circulating molecular signatures that distinguish infected pancreatic necrosis from sterile necrosis. Laboratory analyses will profile candidate biomarkers (for example inflammatory and infection-related proteins and nucleic acids) and correlate signatures with imaging, microbiology, and clinical outcomes. The goal is to develop a blood-based panel that could help identify infection earlier and more accurately than current methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged \>18 years.
* Diagnosis of NP based on CECT.

Exclusion Criteria:

* recurrent AP
* pancreatic cancer
* pregnancy, lactation
* solid organ transplant
* immunodeficiency disorders like AIDS.

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Guru Trikudanatham, MD — University of Minnesota
• Study coordinator: Petr Vanek, MD, PhD
• Email: pvanek@umn.edu

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.