Blood-flow restriction training with eccentric loading
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (E-BFR): a Randomised Crossover Study in Healthy Subjects
This study tests if a new way of training that combines blood-flow restriction with eccentric exercises can help healthy adults build muscle strength just as well, but in a more comfortable way than traditional methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Zurich Academic / other |
| Locations | 1 site (Zurich) |
| Trial ID | NCT06856629 on ClinicalTrials.gov |
What this trial studies
This study investigates the immediate physiological and perceptual responses to blood-flow restriction training combined with eccentric loading, comparing it to traditional eccentric training. The goal is to determine if this approach can achieve similar or superior gains in muscle strength while being more tolerable for participants. Healthy individuals aged 18 and older will be recruited to participate in the study, which will involve different training interventions. The study aims to provide insights into how these training methods affect muscle performance and perception during exercise.
Who should consider this trial
Good fit: Ideal candidates for this study are clinically healthy individuals aged 18 and older.
Not a fit: Patients with physical or intellectual impairments, pain during exercise, or a history of thromboembolic events may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could offer a more accessible and effective strength training method for a wider range of individuals.
How similar studies have performed: While blood-flow restriction training has been studied, the specific combination with eccentric loading is a novel approach that has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically Healthy Exclusion Criteria: * Physical or intellectual impairment precluding informed consent or protocol adherence * Pain during exercise of any origin * History of thromboembolic event in the lower extremity * Known pregnancy (no testing is carried out)
Where this trial is running
Zurich
- University of Zurich — Zurich, Switzerland (Recruiting)
Study contacts
- Study coordinator: Dario Kohlbrenner, PhD
- Email: dario.kohlbrenner@uzh.ch
- Phone: +41 44 634 60 33
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.