Blood flow restriction training for people with multiple sclerosis

(Effect of Blood Flow Restriction Training on Muscle Strength and Gait Performance in Multiple Sclerosis Patients).

This study tests if blood flow restriction training can help people with multiple sclerosis get stronger and move better.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 48 (estimated)
• Ages: 18 Years to 45 Years
• Sex: All
• Sponsor: Cairo University (other)
• Locations: 1 site (Giza)
• Trial ID: NCT06143930 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of blood flow restriction (BFR) training on strength and physical function in patients with multiple sclerosis (MS). Traditional resistance training has shown benefits for MS patients, but fatigue limits its effectiveness. By applying BFR, the study aims to enhance muscle strength and improve lower extremity function in individuals with relapsing and remitting MS. The research seeks to fill gaps in existing literature regarding the use of BFR in this population.

Who should consider this trial

Good fit: Ideal candidates are individuals diagnosed with relapsing and remitting multiple sclerosis who can walk at least 100 meters and have an EDSS score between 2.5 and 5.5.

Not a fit: Patients with other neurological or orthopedic issues, systemic diseases, cognitive impairments, or those in an acute relapse stage may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve muscle strength and physical function for patients with multiple sclerosis.

How similar studies have performed: While BFR training has shown promise in other neurological populations, its application in multiple sclerosis is relatively novel and under-researched.

Eligibility criteria

Inclusion Criteria:

1. Patients were diagnosed with MS by a neurologist according to McDonald's criteria 2010
2. Expanded Disability Status Scale (EDSS) scores ranging from 2.5 to 5.5 .
3. Patient able to walk 100 meters or more.
4. No change within MS specific medication three months from the study.
5. Last Ms Attack from more than two months.

Exclusion Criteria:

1. Multiple sclerosis patients with other neurological or orthopedic problems.
2. Multiple sclerosis patients with systemic problems (cardiovascular or pulmonary diseases...).
3. Patients with cognitive impairment.
4. Pregnant female patients.
5. Patients in acute relapse stage.

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Where this trial is running

Giza

• Faculty of physical therapy — Giza, Egypt (RECRUITING)

Study contacts

• Principal investigator: Habiba Zienhom — Cairo University
• Study coordinator: Habiba Zienhom

Conditions: MS