Blood flow restriction training for knee osteoarthritis

Effects of Blood Flow Restriction Training With Low Intensity Exercises on Pain,Range of Motion and Quality of Life in Knee Osteoarthritis

Not applicable Interventional Riphah International University · NCT06502587

This study is testing if combining blood flow restriction training with low-intensity exercises can help people with knee osteoarthritis feel less pain and improve their movement and quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment36 (estimated)
Ages40 Years to 65 Years
SexAll
SponsorRiphah International University Academic / other
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06502587 on ClinicalTrials.gov

What this trial studies

This study examines the effects of blood flow restriction training combined with low intensity exercises on pain, range of motion, and quality of life in patients with knee osteoarthritis. Conducted at Lahore General Hospital, it involves a randomized clinical trial with 36 participants aged 40-65 years. Participants will be divided into two groups, with one receiving blood flow restriction training alongside standard ultrasound therapy, while the other group will receive only the standard treatment. The outcomes will be measured using various scales before and after a 4-week intervention period.

Who should consider this trial

Good fit: Ideal candidates are males and females aged 40 to 65 years diagnosed with knee osteoarthritis and experiencing moderate to severe pain.

Not a fit: Patients with comorbid conditions such as hypertension, diabetes, or obesity may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce pain and improve the quality of life for patients with knee osteoarthritis.

How similar studies have performed: Previous studies have shown promising results with blood flow restriction training in various populations, suggesting potential success for this approach in knee osteoarthritis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Both Male and Female age between 40 to 65 years diagnosed with womac ostearthritis index having acute knee pain.
* Patients with history of osteoarthritis (of grade 1 and 2 with KL(kellgren and Lawerence)) grading system for knee Osteoarthritis
* Pain in and around knee measuring through Numeric Pain rating Scale(NPRS)\>4(14)

Exclusion Criteria:Patient with history of

* hypertension
* diabetes
* sickle cell anemia
* renal compromise
* obesity
* open fracture,
* increased intracranial pressure
* pregnancy
* cancer or tumor,
* extremity with dialysis access,
* extremity fracture
* peripheral vascular compromise
* DVT(Deep vein thrombosis) \& pulmonary embolism deformity of hip \& back

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knee OsteoarthritisBlood flow restriction trainingPainQuality of lifeRange of motion
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.