Clinical trial Recruiting at 1 site Interventional Ages 14 to 18

Blood Flow Restriction Nordic Hamstring in Elite Adolescent Athletes

Official title: Comparison of Hamstring Muscle Oxygenation Responses During Nordic Hamstring Exercise and Blood Flow Restriction Nordic Hamstring Exercise in Elite Adolescent Athletes: A Crossover Experimental Study

Run by Toros University · NCT07715786 · Data updated 2026-11-12

This crossover study tests whether adding blood flow restriction to the Nordic Hamstring Exercise changes muscle oxygenation in elite adolescent athletes aged 14–18.

Quick facts

Study typeInterventional
Ages14 Years to 18 Years
SexAll
Enrollment24 (estimated)
SponsorToros University
Academic / other
Locations1 site (Adana)
StatusRecruiting
StartedJuly 1, 2026
Main results expectedJuly 2027
Study endsAugust 2027
Registry record updatedJuly 20, 2026
Trial IDNCT07715786 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are elite adolescent athletes aged 14–18 with at least 3 years of regular training and no recent hamstring injuries.

Probably not a fit

Participants with recent lower-extremity injuries, significant medical conditions, or contraindications to blood flow restriction may not benefit from this intervention.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this crossover study, elite adolescent athletes will perform both the standard Nordic Hamstring Exercise and the same exercise with blood flow restriction in random order, separated by a 7-day washout. Muscle oxygen saturation and total hemoglobin will be monitored continuously with wearable near-infrared spectroscopy, alongside lactate, perceived exertion, and performance variables. The aim is to understand the acute physiological effects of combining blood flow restriction with eccentric hamstring work in healthy, trained youth. Findings could inform safer and more effective training approaches for this population. The study is conducted at the Adana Olympic Preparation Center with Toros University as lead sponsor.

Why it matters

Potential benefit: If successful, this approach could help tailor hamstring training to optimize metabolic stress and muscle response in young high-level athletes.

How similar studies have gone: Previous work suggests that BFR can alter muscle oxygenation during exercise, but evidence in elite adolescent populations performing NHE is limited and this study explores novelty in this specific combination.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Elite adolescent athletes aged 14 to 18 years.
* Licensed athletes with at least 3 years of regular sports participation.
* Currently participating in a regular weekly training program.
* Physically able to complete the Nordic Hamstring Exercise and study testing protocol.
* Willing to participate in the study.
* Able to provide written informed consent.
* For participants younger than 18 years, written informed consent provided by a parent or legal guardian and assent provided by the participant.

Exclusion Criteria:

* Hamstring injury within the previous 6 months.
* Lower extremity surgery within the previous 6 months.
* Current lower extremity pain or musculoskeletal injury that may interfere with exercise performance.
* Cardiovascular, vascular, neurological, or other medical conditions that may contraindicate blood flow restriction exercise.
* Presence of skin lesions or conditions preventing placement of the blood flow restriction cuff or MOXY sensor.
* Inability to complete either exercise condition or follow the study protocol.

Where it's running

  • Adana Olympic Preparation Center
    Adana, Turkey (Türkiye)
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.