Blood biomarker testing for mesenteric ischemia
Mesenteric Ischemia Markers Study In The Presence Of Mesenteric Arteries Disease
This study will test whether specific blood biomarkers can reliably detect mesenteric ischemia and distinguish non‑transmural from transmural disease in adults with suspected mesenteric artery problems.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Belarusian State Medical University Academic / other |
| Locations | 1 site (Minsk) |
| Trial ID | NCT07460700 on ClinicalTrials.gov |
What this trial studies
This prospective interventional study will collect blood samples from adults who have undergone angiographic visualization and are suspected of having mesenteric arterial disease. Investigators will measure multiple candidate biomarkers and analyze combinations to identify signatures that separate non‑transmural from transmural ischemia. The protocol emphasizes methodological rigor to address prior low‑quality and heterogeneous evidence. The goal is to produce validated biomarker panels that could be used for earlier risk stratification in clinical practice.
Who should consider this trial
Good fit: Adults aged 18 or older with angiographic visualization and clinical suspicion of mesenteric arterial disease who can give informed consent and do not have pregnancy or disqualifying prior major abdominal/mesenteric surgery are ideal candidates.
Not a fit: Patients who do not have mesenteric ischemia, who are pregnant, who have had major prior operations on the mesenteric arteries or digestive organs, or who cannot consent or attend the study site are unlikely to receive benefit.
Why it matters
Potential benefit: If successful, validated biomarkers could enable earlier diagnosis and treatment of mesenteric ischemia, potentially reducing morbidity and mortality.
How similar studies have performed: Previous studies of blood biomarkers for mesenteric ischemia have been limited and produced inconsistent, low‑quality results, so reliable validation is still lacking.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older, all sex * Initial decision, the presence of angio-visualisation of the MA and suspicion of mesenteric arteries diseases * Patient's consent to participate in the study * No pregnancy, no history of major operations on MA, the gastrointestinal tract and digestive organs (except appendectomy, endoscopic polypectomy). Exclusion Criteria: * Consent declined by patient or relatives * Failure to meet inclusion criteria
Where this trial is running
Minsk
- Belarusian State Medical University — Minsk, Belarus (Recruiting)
Study contacts
- Study coordinator: Hleb But-Husaim, PhD
- Email: dr.buthusaim@gmail.com
- Phone: +375256139407
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.