Bleeding rates in patients on blood thinners undergoing endoscopy
Official title: Bleeding Rate After EGD and Colonoscopy in Patients Who Continue to Take Antithrombotic Agents
Run by Showa Inan General Hospital · NCT02594813 · Data updated 2026-11-12
This study looks at how often patients on blood thinners bleed during endoscopy procedures like EGD and colonoscopy to see if it's safe for them to have these tests.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 90 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Showa Inan General Hospital Academic / other |
| Locations | 1 site (Komagane) |
| Status | Recruiting |
| Started | November 2015 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | May 15, 2025 |
| Trial ID | NCT02594813 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who are on antithrombotic medications and are scheduled for EGD or colonoscopy.
✕Probably not a fit
Patients who undergo prophylactic clipping after biopsy or polypectomy, or those classified as American Society of Anesthesiologists physical status class IV or V, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the bleeding rates associated with esophagogastroduodenoscopy (EGD) and colonoscopy in patients who continue to take antithrombotic medications. It focuses on both immediate and delayed bleeding events that may require endoscopic intervention, such as hemostatic clipping. The study aims to define the incidence of bleeding and assess the condition of submucosal arteries in excised specimens when bleeding occurs. By monitoring these outcomes, the study seeks to provide insights into the safety of performing endoscopic procedures in patients on blood thinners.
Why it matters
Potential benefit: If successful, this study could help establish safer guidelines for performing endoscopic procedures in patients taking antithrombotic agents.
How similar studies have gone: While there may be studies on bleeding rates in endoscopy, this specific focus on patients continuing antithrombotic therapy is less common, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion criteria is all patients who continue to take antithrombotic drugs and undergo EGD or colonoscopy Exclusion Criteria: * Patients who take prophylactic clipping after biopsy or polypectomy American Society of Anesthesiologists physical status of class IV or V
Where it's running
-
Showa Inan General Hospital
Komagane, Japan Recruiting
Study contacts
- Principal investigator: Akira Horiuchi, MD — Showa Inan General Hospital
- Study coordinator: Akira Horiuchi, MD
- Email: horiuchi.akira@sihp.jp
- Phone: 0265822121
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.