BLa80 and LRa05 probiotics and blood metabolite changes in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls healthy adults aged 18–60 and assigns them to receive BLa80, LRa05, or placebo. Blood samples will be analyzed using metabolomics to identify food-derived metabolites and compare changes between groups. Key exclusions include recent antibiotic or probiotic use and major gastrointestinal, metabolic, immune, cardiac, liver, neurological, or psychiatric conditions. The research requires in-person visits at The First Affiliated Hospital, Sun Yat-sen University for dosing and sample collection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Male or female participants aged 18 to 60 years;
2. Healthy individuals;
3. Participants must provide written informed consent.

Exclusion Criteria:

1. History of gastrointestinal surgery, other gastrointestinal diseases, metabolic disorders, immunodeficiency, hyperthyroidism, or cardiac or liver disease;
2. Use of immunosuppressants;
3. Pregnant or breastfeeding women;
4. Participants who have taken antibiotics or probiotics within the previous 3 months;
5. Planned surgery during the study period;
6. Patients with neurological disorders or psychiatric illness.

Where it's running

• The First Affiliated Hospttal, Sun Yat-sen University
  Guangzhou, Guangdong, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.