Biological and pathophysiological features linked to sexual orientation in men
Official title: Investigating the Pathophysiological Nature of Homosexuality Patients in Egypt, England, China, and Mexico: Multicenter Study.
Run by Tanta University · NCT05897177 · Data updated 2026-11-12
This observational project will try to see whether certain biological markers and experiences of stigma differ in adult men who are gay compared with other men.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | Men only |
| Enrollment | 500 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Status | Recruiting |
| Started | July 20, 2023 |
| Main results expected | November 20, 2027 |
| Study ends | April 20, 2028 |
| Registry record updated | March 16, 2026 |
| Trial ID | NCT05897177 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are men age 18 or older who are not taking testosterone or anabolic steroids, are HIV-negative, do not report multi-sexual behavior, and do not have an addictive disorder.
✕Probably not a fit
People under 18, women, men taking testosterone or anabolic steroids, people living with HIV, individuals reporting bisexual/multi-sexual behavior, or those with current addictive disorders are excluded and would not be expected to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational protocol enrolls adult men to collect clinical, biological, and self-report data, including the Subjective Scale of Stigma and Discrimination (SISD), to explore links between biological markers and male homosexual behavior. Eligibility excludes men taking testosterone or anabolic steroids, people with HIV, those reporting multi-sexual (bisexual) behavior, and individuals with addictive disorders. Data appear to be collected at a single site in Egypt (Tanta University) with no experimental treatments or interventions administered. The aim is to describe associations rather than to test a therapeutic intervention.
Why it matters
Potential benefit: If clear patterns are found, the work could help clarify biological contributors to male sexual orientation and inform clinical awareness and public discussion.
How similar studies have gone: Prior research has reported genetic, prenatal hormonal, and neuroanatomical associations with sexual orientation, but findings have been mixed and remain scientifically and socially controversial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Male will be included Exclusion Criteria: * Patients taking testosterone or its derivative. * Patients taking anabolic steroids. * Multi-sexual behaviours. * HIV patients. * not having and addictive disorder
Where it's running
-
Tanta Unuversity
Tanta, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.