Biofeedback training for children with idiopathic infantile nystagmus

Biofeedback in Idiopathic Infantile Nystagmus Syndrome

NA · University of Toronto · NCT04142307

This study is testing if biofeedback training can help children with idiopathic infantile nystagmus improve their vision and control their eye movements better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment34 (estimated)
Ages5 Years to 17 Years
SexAll
SponsorUniversity of Toronto (other)
Locations1 site (Toronto, Ontario)
Trial IDNCT04142307 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of biofeedback training (BT) for children diagnosed with idiopathic infantile nystagmus (IIN), a condition that affects eye movement and vision. The approach involves using advanced microperimetry instruments to provide real-time feedback during eye movement control training. The goal is to systematically assess the impact of BT on visual acuity and eye movement stability in affected children, ultimately formulating guidelines for its clinical application. Traditional therapies have focused on surgical and optical interventions, making this a novel approach in low vision rehabilitation.

Who should consider this trial

Good fit: Ideal candidates for this study are children diagnosed with idiopathic infantile nystagmus who can follow visual and auditory training instructions.

Not a fit: Patients with ocular diseases unrelated to nystagmus or those with other types of nystagmus may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve visual function and quality of life for children with idiopathic infantile nystagmus.

How similar studies have performed: Previous laboratory studies have shown positive outcomes using biofeedback techniques in nystagmus cases, indicating potential for success in this clinical application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed as Infantile idiopathic nystagmus (IIN)
* Ability to follow the visual and auditory stimuli and training instructions

Exclusion Criteria:

* Ocular diseases not related to the nystagmus physiopathology
* Both eyes with media opacity that impairs microperimetry testing
* Peripheral nystagmus cases
* Other types of nystagmus than IIN
* Inability to perform during testing and training

Where this trial is running

Toronto, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Low Vision in Children, biofeedback, vision rehabilitation, nystagmus, paediatric

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.