Bilateral robot-assisted rehabilitation for upper limb recovery in subacute stroke patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of Bilateral Robot-Assisted Therapy (BRAT) in improving motor recovery of the upper limbs in individuals with subacute stroke. Participants will be randomly assigned to either the experimental group receiving BRAT or a control group undergoing conventional rehabilitation. The study aims to measure improvements in motor function using the Fugl-Meyer Assessment - Upper Limb (FMA-UL). The trial seeks to determine if robotic rehabilitation can provide better outcomes compared to standard arm re-education methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Both sexes;
* Age \>18 years;
* Unilateral hemipyramidal syndrome as demonstrated by a brain CT or MRI;
* Distance from acute event \< 6 months;
* Modified Ashworth Scale (MAS) of shoulder, elbow, and wrist \<3;
* Ability to understand and sign the informed consent for the study;
* Ability to perform the study procedures.

Exclusion Criteria:

* Unstable general clinical conditions;
* Bilateral pyramidal hemisyndrome severe visual impairment;
* Recent injection of Botulinum Toxin to the affected upper limb or planned for the duration of the study;
* Interruption of treatment for 1 week or 5 consecutive sessions;
* Inability to adhere to the exercise program due to poor compliance;
* Presence of neurological pathologies superimposed on the stroke event, psychiatric complications or personality disorders;
* Presence of osteoarticular and neuromuscular pathologies that may compromise the motor skills of the upper limb;
* Participants who have not signed the informed consent to the study.

Where it's running

• IRCCS San Raffaele Roma
  Rome, Italy, Italy Recruiting
• San Raffaele Cassino
  Cassino, Italy, Italy Not yet recruiting
• San Raffaele Sulmona
  Sulmona, Italy, Italy Not yet recruiting

Study contacts

• Principal investigator: Dr. Sanaz Pournajaf, DPT — IRCCS San Raffaele Roma
• Study coordinator: Dr. Sanaz Pournajaf, DPT
• Email: sanaz.pournajaf@sanraffaele.it
• Phone: +39-06-52252405

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Dual-task balance training plus computer-based cognitive training after stroke

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.