Biannual breath and blood marker tracking for COPD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Over 12 months, participants attend three visits (baseline, 6 months, 12 months) for routine lung function tests, symptom questionnaires, a simple breath nitric oxide (FeNO) test, and a small extra blood draw to measure eosinophils. The study will track how airway inflammation markers, lung function, and symptoms change over time and compare trajectories between people who experience exacerbations and those who remain stable. All procedures except the extra blood draw are part of standard COPD follow-up and participation does not change usual treatment. The goal is to map marker trends that could inform future personalized management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥ 40 years
* Diagnosed with COPD according to GOLD criteria
* Attending routine follow-up visits every 6 months
* Ability to provide informed consent

Exclusion Criteria:

* Recent respiratory tract infection or exacerbation (either moderate or se-vere) (\<4 weeks before inclusion)
* Dominant asthmatic phenotype (ACO with asthma predominance)
* Severe comorbidities interfering with participation or follow-up

Where it's running

• Universitair Ziekenhuis Brussel
  Jette, Belgium Recruiting

Study contacts

• Study coordinator: Naomi Michotte, MD
• Email: pneumologie@uzbrussel.be
• Phone: 024776841

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.